SLC10A1 antibody

SLC10A1 antibody

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  • ¥780 - 2200
  • 康朗生物
  • kl-1958R
  • 中国/美国/德国
  • 2025年07月13日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /test ICC=1:100-500 IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Dog, Horse, Rabbit,
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    • 详细信息
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-1958R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      SLC10A1 antibody

    • 抗体名

      钠离子/牛磺胆酸共转运蛋白抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Dog, Horse, Rabbit,

    • 免疫原

      KLH conjugated synthetic peptide derived from human NTCP:21-120/349

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /test ICC=1:100-500 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      50ul 100ul 200ul

    SLC10A1 antibody
    中文名称 钠离子/牛磺胆酸共转运蛋白抗体
    别    名 Na+/taurocholate Cotransporting Polypeptide; Na(+)/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na / bile acid cotransporter; Na / taurocholate transport protein; Na(+)/taurocholate transport protein; NTCP; NTCP1; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; Slc10a1 protein; Slc10a1; SBACT; SLC10A1; NTCP_HUMAN.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 免疫学  信号转导  转运蛋白  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /test ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 38kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human NTCP:21-120/349 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization(SLC10A2; MIM 601295), and the other being found in the basolateral membranes of hepatocytes (SLC10A1).[supplied by OMIM]

    Function:
    The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.

    Subcellular Location:
    Membrane; Multi-pass membrane protein.

    Tissue Specificity:
    Liver and kidney

    Similarity:
    Belongs to the sodium:bile acid symporter family.

    SWISS:
    Q14973

    Gene ID:
    6554

    Database links:

    Entrez Gene: 6554 Human

    Entrez Gene: 20493 Mouse

    Entrez Gene: 24777 Rat

    Omim: 182396 Human

    SwissProt: Q14973 Human

    SwissProt: O08705 Mouse

    SwissProt: P26435 Rat

    Unigene: 952 Human

    Unigene: 341781 Mouse

    Unigene: 9913 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    NTCP(钠离子/牛磺胆酸共转运蛋白)(钠离子-牛磺胆酸共转运多肽)Na+/taurocholate Cotransporting Polypeptide是 肝脏的胆汁酸盐吸收主要是钠离子依赖性转运子NTCP介导的,主要吸收牛磺胆酸,是肝细胞特有的一种转运载体,分布在肝细胞基侧膜在肝小叶和肝的腺泡表达较多。
    有学者认为:NTCP是乙肝病毒的细胞表面受体分子,是HBV和HDV的功能受体,这些研究将有待于科研人员的进一步证实。
    产品图片 SLC10A1 antibody
    Sample: K562 (human)cell Lysate at 40 ug
    Primary: Anti- SLC10A1 (bs-1958R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 38 kD
    Observed band size: 48 kD

    SLC10A1 antibody
    Tissue/cell: Siha cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (SLC10A1) Polyclonal Antibody, Unconjugated (bs-1958R) 1:200, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody (bs-0295G-FITC) at 37°C for 90 minutes, DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei.
    SLC10A1 antibody
    Tissue/cell: HT1080 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (SLC10A1) Polyclonal Antibody, Unconjugated (bs-1958R) 1:200, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody (bs-0295G-FITC) at 37°C for 90 minutes, DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei.
    SLC10A1 antibody
    Blank control: 293T(blue).
    Primary Antibody:Rabbit Anti-SLC10A1 antibody(bs-1958R), Dilution: 1μg in 100 1μL 1X PBS containing 0.5% BSA(green);
    Isotype Control Antibody: Rabbit IgG(orange) used under the same conditions );
    Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.

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