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Histone H3.1 antibody

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  • ¥1380 - 2200
  • 康朗生物
  • kl-17422R
  • 中国/美国/德国
  • 2026年01月08日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500
  • Rabbit
  • Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Chimpanzee,
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      上海康朗生物科技有限公司

    • 库存

      大量

    • 目录编号

      kl-17422R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      12个月

    • 抗体英文名

      Histone H3.1 antibody

    • 抗体名

      组蛋白H3.1抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Chimpanzee,

    • 免疫原

      KLH conjugated synthetic peptide derived from human Histone H3.1:71-136/136

    • 亚型

      IgG

    • 形态

      冻干粉或液体

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul 200ul

    Histone H3.1 antibody
    中文名称 组蛋白H3.1抗体
    别    名 H3 histone family, member A; H3 histone family, member B; H3 histone family, member C; H3 histone family, member D; H3 histone family, member E; H3 histone family, member F; H3 histone family, member G; H3 histone family, member H; H3 histone family, member I; H3 histone family, member J; H3 histone family, member K; H3 histone family, member L; H3.1; H3.f; H3/A; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3/l; H31_HUMAN; H3F1K; H3FA; H3FB; H3FC; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; HIST1 cluster H3A; HIST1 cluster H3B; HIST1 cluster H3C; HIST1 cluster H3D; HIST1 cluster H3E; HIST1 cluster H3F; HIST1 cluster H3G; HIST1 cluster H3I; HIST1 cluster H3J; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; histone 1, H3a; histone 1, H3b; Histone 1, H3c; Histone 1, H3e; histone 1, H3f; histone 1, H3g; histone 1, H3h; histone 1, H3i; histone 1, H3j; histone cluster 1, H3a; histone cluster 1, H3b; Histone cluster 1, H3c; Histone cluster 1, H3e; histone cluster 1, H3g; histone cluster 1, H3h; histone cluster 1, H3i; histone cluster 1, H3j; Histone gene cluster 1 H3A; Histone gene cluster 1 H3B; Histone gene cluster 1 H3E; Histone gene cluster 1 H3F; Histone gene cluster 1 H3G; Histone gene cluster 1, H3; Histone gene cluster 1, H3C; Histone gene cluster 1, H3D; Histone gene cluster 1, H3I; Histone gene cluster 1, H3IH; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l  
    规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 100ul  200ul
    研究领域 细胞生物  表观遗传学  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Chimpanzee, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 15kDa
    细胞定位 细胞核 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human Histone H3.1:71-136/136 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]

    Function:
    Histone H3.1 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodelling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3 H4 heterotetramer and two H2A H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

    Subcellular Location:
    Nuclear

    Similarity:
    Belongs to the histone H3 family.

    Gene ID:
    8350

    Database links:

    Entrez Gene: 8350 Human

    Entrez Gene: 8351 Human

    Entrez Gene: 8352 Human

    Entrez Gene: 8353 Human

    Entrez Gene: 8354 Human

    Entrez Gene: 8355 Human

    Entrez Gene: 8356 Human

    Entrez Gene: 8357 Human

    Entrez Gene: 8358 Human

    Entrez Gene: 8968 Human

    Entrez Gene: 319148 Mouse

    Entrez Gene: 319151 Mouse

    Entrez Gene: 319152 Mouse

    Entrez Gene: 319153 Mouse

    Entrez Gene: 360198 Mouse

    Entrez Gene: 97908 Mouse

    Omim: 602810 Human

    Omim: 602811 Human

    Omim: 602812 Human

    Omim: 602813 Human

    Omim: 602814 Human

    Omim: 602815 Human

    Omim: 602816 Human

    Omim: 602817 Human

    Omim: 602818 Human

    Omim: 602819 Human

    SwissProt: P68431 Human

    SwissProt: P68433 Mouse

    Unigene: 132854 Human

    Unigene: 247813 Human

    Unigene: 247814 Human

    Unigene: 248176 Human

    Unigene: 443021 Human

    Unigene: 484990 Human

    Unigene: 532144 Human

    Unigene: 533292 Human

    Unigene: 546315 Human

    Unigene: 586261 Human

    Unigene: 591778 Human

    Unigene: 626666 Human

    Unigene: 221301 Mouse

    Unigene: 261657 Mouse

    Unigene: 377874 Mouse

    Unigene: 390558 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 产品细节图片1
    Sample:A549 Cell (Human) Lysate at 40 ug
    Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 15kD
    Observed band size: 15kD

    产品细节图片2
    Sample:TT Cell (Human) Lysate at 40 ug
    Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 15kD
    Observed band size: 15kD

    产品细节图片3
    Sample:Stomach (Mouse) Lysate at 40 ug
    Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 15kD
    Observed band size: 15kD

    产品细节图片4
    Sample:U251 Cell (Human) Lysate at 40 ug
    Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 15kD
    Observed band size: 15kD

    产品细节图片5
    Sample:A431 Cell(Human)Lysate at 40 ug
    Primary: Anti-Histone H3.1(bs-17422R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 15kD
    Observed band size: 15kD

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