- ￥1195
- Peprotech
- 315-02-2ug
- 美国
- 2025年12月12日
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- 供应商：
嵘崴达
- 库存：
需确认
- 英文名：
Mouse M-CSF Recombinant Protein, PeproTech®
Product Details
Description:
M-CSF is a potent hematopoietic factor produced by a variety of cells, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival for blood monocytes, tissue macrophages, and their respective progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness and fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. Human M-CSF is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant Murine M-CSF is a 36.4 kDa homodimeric protein consisting of two 156 amino acid polypeptide subunits.
Source: E.coli
Synonyms: Macrophage Colony Stimulating Factor, CSF-1, MGI-IM
AA Sequence (monomer): MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of M-NFS-60 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
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ABCAM试剂，国内现货三天左右，期货四周左右。
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OXOID，BD培养基货期八周左右，部分现货。
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文献和实验持续激活的方式，而增强抗感染天然免疫应答反应)于2011年3月27日发表在《自然—免疫学》(Nature immunology). Nature immunology是Nature的子刊.其目前的影响因子为26。 这篇文章用到Peprotech的Recombinant Murine M-CSF(重组小鼠巨噬细胞集落刺激因子)。具体方法是:用终浓度为50 ng/ml 巨噬细胞集落刺激因子（M-CSF）的培养液培养骨髓细胞, 将骨髓细胞体外诱导分化成巨噬细胞。 并且，用到
(9 ). Because its systemic administration was shown to mediate the regression of some mouse tumors (10 ), TNF-α has attracted much attention as a potential antitumor reagent (11 ). However, the problem of its dose-dependent toxicity has been particularly apparent in human
Preparation of Recombinant Protein Spotted Arrays for Proteome‐Wide Identification of Kinase Targets
Arabidopsis protein microarrays. Proc. Natl. Acad. Sci. U.S.A. 104:4730‐4735. Ptacek, J., Devgan, G., Michaud, G., Zhu, H., Zhu, X., Fasolo, J., Guo, H., Jona, G., Breitkreutz
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