qPCR & SNP Genotyping
LGC Biosearch Technologies offers a variety of probe and primer types for real-time qPCR, including dual-labeled BHQ® probes, BHQplus® probes, Molecular Beacons, and Scorpions® primers.
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LGC Biosearch Technologies
上海钰博生物科技有限公司
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LGC Biosearch Technologies是专业性荧光定量PCR探针合成及标记服务公司,提供与世界上各种荧光定量PCR仪配套的探标记方式及荧光素。
LGC Biosearch Technologies的根源可以追溯到1978年,现任总裁兼首席执行官罗恩 - 库克,博士创立了“Biosearch”,为新兴的生物技术产业提供研究工具。在20世纪80年代,Biosearch自主研发固相DNA合成器,如SAM I, the Cyclone, Biosearch 8700 and Biosearch 8800 Prep。这些生产制造的寡核苷酸的技术,催生新寡核苷酸技术的发展。最引人注目的是1982年,Kary Mullis在Cetus 公司使用了BiosearchSAM I合成DNA创造使用的寡核苷酸,其最终导致的聚合酶链反应(PCR)的发现。
LGC Biosearch Technologies offers a variety of probe and primer types for real-time qPCR, including dual-labeled BHQ® probes, BHQplus® probes, Molecular Beacons, and Scorpions® primers.
Whether you require labeled or unlabeled oligos, we can meet your exact needs as we offer more custom modifications than any other oligo supplier at a cost well below the prevailing market rate.
Stellaris® RNA FISH is a RNA visualization method that allows simultaneous detection, localization, and quantification of individual mRNA molecules at the cellular level in fixed samples. This novel RNA FISH technology represents a fast and easy-to-use method to achieve conclusive results through compelling images of RNA expression.
We offer an extensive range of products for DNA and RNA synthesis including: synthesis supports, columns for 3' labeling and specialty amidites. These products are available for all of our fluorophores and quenchers as well as for many non-fluorescent labels.
We offer a line of immunochemicals which include hapten reporter groups and protein, FICOLL, and fluorophore conjugates.
Find a quick capability overview of LGC Biosearch Technologies and learn more about our products and the markets we serve.
LGC Biosearch Technologies, a division of LGC Group, is a global leader in the design, development, and manufacture of sophisticated, custom oligonucleotide-based tools and associated reagents for the molecular diagnostic, research and applied markets. LGC Biosearch is a vertically integrated organization with locations in the US, Denmark, and Germany. Controlled-pore glass manufacturing, a critical component for oligo synthesis is located in Steinach, Germany. Research-grade oligo manufacturing primarily takes place in Petaluma, California and Århus, Denmark while production for the GMP and Commercial Services program is situated in the cGMP facility based in Novato, California.
LGC Biosearch’s Quality Management System is fully compliant with ISO 9001:2008 and the cGMP production facility is ISO 13485:2003 certified and compliant with 21 CFR Part 820 as applicable. LGC Biosearch fully understands that quality is of utmost importance to customers as poor quality reagents and oligos can ruin even the best-designed assays. Visit our Quality webpageto learn more about LGC Biosearch’s certifications.
Since the early 80s, innovators at LGC Biosearch have refined and continue to perfect the chemistry of oligonucleotide synthesis to accelerate the discovery and application of genomic information. LGC Biosearch’s unmatched selection of oligo modifications is complemented by demonstrated expertise in the design and manufacture of fluorogenic probes and primers. Products include fluorophores (CAL Fluor®, Quasar® and Pulsar® dyes) and dark quenchers (BHQ® also known as Black Hole Quencher® dyes) to be included in custom-synthesized probe formats for real-time PCR, qPCR, end-point PCR, Stellaris® RNA FISH, and other genomic-based applications. LGC Biosearch’s markets include pharmaceutical, in vitro diagnostics, biotechnology, agricultural biotechnology, environmental and food testing, public health, and biodefense sectors.
LGC Biosearch welcomes the opportunity to work with innovators worldwide who enable new inventions that advance the frontier of biotechnology and enthusiastic team players who support continued growth of the business. Please visit our Careers webpage to review current job opportunities.
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文献和实验3′‐Modified Oligonucleotides and their Conjugates
Oligonucleotides Materials 1000 Å aminopropyl‐conjugated controlled‐pore glass (aminopropyl‐CPG; Biosearch Technologies
最大吸光值:453 nm 摩尔消光系数:32.000 M−1 cm−1 分子量:399.2 g/mol BHQ1 – Dark Quencher 480-580 nm BHQ1是Biosearch Technologies公司的黑洞淬灭基团之一,对于双标探针、分子信标和FRET探针非常有效,对绿色至黑色发射光谱中的所有染料都有极好的光谱重叠效应。 淬灭范围: 480-580 nm 最大吸光
光素。 淬灭范围: 400-550 nm 最大吸光值:453 nm 摩尔消光系数:32.000 M−1 cm−1 分子量:399.2 g/mol BHQ1 – Dark Quencher 480-580 nm BHQ1是Biosearch Technologies公司的黑洞淬灭基团之一,对于双标探针、分子信标和FRET探针非常有效,对绿色至黑色发射光谱中的所有染料都有极好的光谱重叠效应
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