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- 详细信息
- 技术资料
- 库存:
380
- 英文名:
Recombinant Human Ephrin A Receptor 2
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人EphA2厂家,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人EphA2厂家
产地:国产|进口
品牌:百奥莱博
英文名:Recombinant Human Ephrin A Receptor 2
规格:10μg|50μg|500μg|1mg
编号:JN1572
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala24-Asn534在C端带有Fc标签。
EphA2质量控制:>95%(还原性SDS-PAGE)
EphA2制剂:冻干品
EphA2保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
EphA2复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于EphA2:
Ephrin type-A receptor 2/EphA2 is a member of the Eph receptor tyrosine kinase family which binds Ephrins A1, 2, 3, 4, and 5. A and B class Eph proteins have a common structural organization. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. EphA2 becomes autophosphorylated following ligand binding and then interacts with SH2 domain-containing PI3-kinase to activate MAPK pathways. Reverse signaling is also propagated through the Ephrin ligand. Transcription of EphA2 is dependent on the expression of E-Cadherin, and can be induced by p53 family transcription factors. EphA2 is upregulated in breast, prostate, and colon cancer vascular endothelium. Its ligand, EphrinA1, is expressed by the local tumor cells. In some cases, EphA2 and EphrinA1 are expressed on the same blood vessels. EphA2 signaling cooperates with VEGF receptor signaling in promoting endothelial cell migration.
除重组人EphA2厂家外,我公司正在打折促销以下产品:
·重组小鼠IFN-gamma R1(CD119)(C端含His标签)
编号:JN1411
英文名称:Recombinant Mouse Interferon gamma Receptor 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ala26-Asp253在C端含有His标签。
IFN-gamma R1/CD119质量控制:>95%(还原性SDS-PAGE)
IFN-gamma R1/CD119制剂:冻干品
IFN-gamma R1/CD119保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
IFN-gamma R1/CD119复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于IFN-gamma R1/CD119:
The tetrameric receptor complex for IFNγ consists of two subunits, IFNGR1 (IFNγ Rα) and IFNGR2 (IFNγ Rβ), through which the dimeric IFN-γ exerts its biological functions, including antiviral, antiproliferation and immune-modulatory activity in mammals. Both IFNGR1 and IFNGR2 are single transmembrane proteins belonging to the class II cytokine family. FNGR1, widely expressed in most host cells, is essential for IFNγ binding, receptor trafficking, and signal transduction. IFNGR1 possesses an intracellular Janus tyrosine kinase (JAK) 1 binding site, a signal transducer and activator of transcription 1 (STAT1) binding site. The resulting STAT1 homodimers translocate from the cytoplasm to the nucleus and bind to the interferon-gamma activated sequence (GAS) promoter to induce expression of downstream interferon stimulated genes (ISGs).
重组人EphA2厂家关键词:Recombinant Human Ephrin A Receptor 2,重组人EphA2蛋白,百奥莱博,重组EphA2,JN1572
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重组人EphA2厂家关键词:Recombinant Human Ephrin A Receptor 2,重组人EphA2蛋白,百奥莱博,重组EphA2,JN1572
·重组人Serpin B5(丝*酸蛋白酶抑制剂B5)
编号:JN1758
英文名称:Recombinant Human Serine Protease Inhibitor-clade B5
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Ser231表达纯化得来。
Serpin B5质量控制:>95%(还原性SDS-PAGE)
Serpin B5制剂:冻干品
Serpin B5保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Serpin B5复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Serpin B5:
Serpin B5 is a secretive protein that belongs to the Serpin (Serine Protease Inhibitor) family and Ov-serpin subfamily. Serpin B5 is expressed in the prostate, testis, intestine, tongue, lung, and thymus. Serpin B5 exhibits no serine protease inhibitory activity. Serpin B5 also functions as tumor suppressor an angiogenesis inhibitor. It has been shown that Serpin B5 blocks the growth, invasion, and metastatic properties of mammary tumors. Furthermore, high expression of Serpin B5 is linked to squamous cell carcinoma in non-small-cell lung cancer.
北京百莱博科技有限公司是重组蛋白产品的专业生产供应销*(代"售")商,恭候您的咨询选购重组人EphA2厂家。
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