北京重组人MANF(含His标签)厂商

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")北京重组人MANF(含His标签)厂商，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：北京重组人MANF(含His标签)厂商
规格：10μg|50μg|500μg|1mg
品牌：百奥莱博
英文名：Recombinant Human Mesencephalic astrocyte-derived neurotrophic factor
产地：国产|进口
编号：JN0208
本品由我们的哺乳动物表达系统制备，目的基因编码的Leu25-Leu182在C端含有His标签。

MANF质量控制：＞95%(还原性SDS-PAGE)。

MANF制剂：冻干品

MANF保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

MANF复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于MANF：
Mesencephalic astrocyte-derived neurotrophic factor(MANF) is a secreted protein which belongs to the ARMET family. MANF selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. It modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. MANF enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. MANF inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. The N-terminal region of ARMET may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response. MANF reduces endoplasmic reticulum (ER) stress and has neurotrophic effects on dopaminergic neurons. Intracortical delivery of recombinant MANF protein protects tissue from ischemic brain injury. MANF has been described as a survival factor for dopaminergic neurons. MANF and a homologous protein, the conserved dopamine neurotrophic factor (CDNF), form a novel evolutionary conserved family of neurotrophic factors. MANF expression was widespread in the nervous system and non-neuronal tissues.

我公司的北京重组人MANF(含His标签)厂商，性价比高，货期短，送货上门，欢迎您来电咨询购买，另外，我公司还生产供应销*(代"售")下列产品：

·重组人SGSH
编号：JN0806
英文名称：Recombinant Human N-Sulphoglucosamine Sulphohydrolase
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg21-Leu502在C端含有His标签。

SGSH质量控制：＞95%(还原性SDS-PAGE)

SGSH制剂：液体

SGSH保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于SGSH：
N-Sulphoglucosamine Sulphohydrolase (SGSH) is an important member of the sulfatase family which is involved in the degradation of heparin sulfate. SGSH binds one calcium ion per subunit as a cofactor. SGSH catalyzes N-sulfo-D-glucosamine and H2O to D-glucosamine and sulfate. SGSH deficiency is result in mucopolysaccharidosis type 3A (MPS3A), a recessive lysosomal storage disease characterized by neurological dysfunction but relatively mild somatic manifestations.

·重组人泛素结合酶E2-V2(UBE2V2)
编号：JN1021
英文名称：Recombinant Human Ubiquitin-Conjugating Enzyme E2 Variant 2
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Asn145在N端含有His标签。

UBE2V2质量控制：＞95%(还原性SDS-PAGE)

UBE2V2制剂：液体

UBE2V2保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于UBE2V2：
Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin.It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.


北京重组人MANF(含His标签)厂商关键词：重组人MANF,含His标签,重组MANF,重组人MANF蛋白,JN0208


·重组错配尿嘧啶DNA糖基化酶(Mug)
编号：JN1944
英文名称：Recombinant E. coli G/U Mismatch-Specific DNA Glycosylase/Mug
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目标蛋白包含序列(Met1-Arg168) of E.coli Mug.

Mug质量控制：＞95%(SEC-HPLC，还原性SDS-PAGE)

Mug制剂：液体

Mug保存：
收到后请置于-20℃以下，可保存长达6个月，避免反复冻融。

关于Mug：
E. coli Mismatch Uracil DNA Glycosylase (Mug protein) is an 18 kDa constitutively expressed protein which belongs to the TDG/mug DNA glycosylase family. It has been proposed that the Mug protein excises 3,N4-ethenocytosine and removes the uracil base from mismatches in the order of U:G>U:A, although the biological role remains unclear. Uracil bases in DNA can arise from deamination of cytosine giving rise to increased spontaneous mutations. The enzyme Uracil-N-Glycosylase removes uracil from the DNA leaving an AP site. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. It is required for DNA damage lesion repair in stationary-phase cells.


北京重组人MANF(含His标签)厂商关键词：重组人MANF,含His标签,重组MANF,重组人MANF蛋白,JN0208


·重组人Cystatin D(胱抑素D)
编号：JN1685
英文名称：Recombinant Human Cystatin D
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly21-Val142在C端含有His标签。

Cystatin D质量控制：＞95%(还原性SDS-PAGE)

Cystatin D制剂：冻干品

Cystatin D保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Cystatin D复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Cystatin D：
Cystatin-D is a protein that in humans is encoded by the CST5 gene. The cystatin superfamily encomp*(代"a")sses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity.

我公司正在火爆促销重组蛋白系列产品，欢迎您的垂询选购北京重组人MANF(含His标签)厂商。