Recombinant Murine IGF-1

Recombinant Murine IGF-1

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  • ¥7206
  • 联迈生物
  • LM6105-1mg
  • 中国/上海
  • 2025年07月05日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 英文名

      Recombinant Murine IGF-1

    • 保质期

      一年

    • 供应商

      上海联迈生物工程有限公司

    • 保存条件

      -20℃或更低温度保存

    • 规格

      1mg

    Recombinant Murine IGF-1
    产品编号 产品名称 产品包装 产品价格
    LM6105-1mg Recombinant Murine IGF-1 1mg 7206.00
     
    Species Gene ID Accession Source Length MW Tag
    Mouse 16000 LM05017 E. coli 70aa 7.7kDa
     
    About this Antibody
    Name Recombinant Murine IGF-1 (Recombinant Murine Insulin-like Growth Factor-1; rMuIGF-1);Recombinant Mouse IGF-1 ; 重组小鼠胰岛素样生长因子1
    Synonyms IGF1; IGF-1; Somatomedin A; Somatomedin C; IBP1; IGF1A; IGFI; IGF-I; IGF-IA; IGF-IB; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; Mechano growth factor; MGF; somatomedin-C; Somatomedin-C
    Purity >97% by SDS-PAGE and HPLC analyses.
    Biological Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using serum free human MCF-7 cells is less than 2ng/ml, corresponding to a specific activity of >5.0×105IU/mg.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Formulation Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.
    Endotoxin Less than 0.1EU/μg of rMuIGF-1 as determined by LAL method.
    Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 100mM HAc to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
    Category Cytokine
    Background The insulin-like growth factors (IGFs) belonged to the insulin gene family, are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. The production of IGF-1 is stimulated by growth hormone (GH) and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signaling pathway post GH receptor including SHP2 and STAT5B. Recombinant murine IGF-1 are globular proteins containing 70 amino acids and 3 intra-molecular disulfide bonds. Mature murine IGF-1 shares 94% and 98%a.a. sequence identity with human and rat IGF-1, respectively.
    Amino Acid Sequence GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKAA
    包装清单:
    产品编号 产品名称 包装
    LM6105-10μg Recombinant Murine IGF-1 10μg
    LM6105-50μg Recombinant Murine IGF-1 50μg
    LM6105-100μg Recombinant Murine IGF-1 100μg
    LM6105-1mg Recombinant Murine IGF-1 1mg
    - 说明书 1
    保存条件:
           -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
    注意事项:
           由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
           本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
           为了您的安全和健康,请穿实验服并戴一次性手套操作。


     

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