Recombinant Murine FGF-8

Recombinant Murine FGF-8

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  • ¥464
  • 联迈生物
  • LM6083-5μg
  • 中国/上海
  • 2025年07月16日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 英文名

      Recombinant Murine FGF-8

    • 保质期

      一年

    • 供应商

      上海联迈生物工程有限公司

    • 保存条件

      -20℃或更低温度保存

    • 规格

      5μg

    Recombinant Murine FGF-8
    产品编号 产品名称 产品包装 产品价格
    LM6083-5μg Recombinant Murine FGF-8 5μg 464.00
     
    Species Gene ID Accession Source Length MW Tag
    Mouse 14179 LM37237 E. coli 246aa 28.1kDa
     
    About this Antibody
    Name Recombinant Murine FGF-8 (Recombinant Murine Fibroblast Growth Factor-8; rMuFGF-8)Recombinant Mouse FGF-8 ; 重组小鼠成纤维细胞生长因子8
    Synonyms AIGF; HBGF-8; AIGFKAL6; Androgen-induced growth factor; FGF-8; fibroblast growth factor 8; fibroblast growth factor 8 (androgen-induced); HBGF-8; Heparin-binding growth factor 8; MGC149376
    Purity >97% by SDS-PAGE and HPLC analyses.
    Biological Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 5.0ng/ml, corresponding to a specific activity of >2.0×105IU/mg in the presence of 10μg/ml of heparin.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Formulation Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, 500mM NaCl.
    Endotoxin Less than 1EU/μg of rMuFGF-8 as determined by LAL method.
    Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
    Category Cytokine
    Background Murine FGF-8 is a heparin binding growth factor belonging to the FGF family, which plays a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. Murine FGF-8 is first purified from an androgen-dependent mouse mammary carcinoma cell line as an androgen induces secretion. Cloning and analysis of the murine FGF8 gene revealed at least eight potential protein isoforms (FGF-8 a-h). Murine FGF-8a and b share 100% amino acid identity with that in humans, and murine FGF-8e and f share 98% amino acid identity with humans. None of the FGF-8 isoforms exhibited activity to FGFR1b, 2b, 3b, but FGFR2c, 3c and FGFR4 can be activated by several FGF-8 isoforms. FGF-8 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration, and it is required for normal brain, eye, ear and limb development during embryogenesis.
    Amino Acid Sequence QVRSAAQKRG PGAGNPADTL GQGHEDRPFG QRSRAGKNFT NPAPNYPEEG SKEQRDSVLP KVTQRHVREQ SLVTDQLSRR LIRTYQLYSR TSGKHVQVLA NKRINAMAED GDPFAKLIVE TDTFGSRVRV RGAETGLYIC MNKKGKLIAK SNGKGKDCVF TEIVLENNYT ALQNAKYEGW YMAFTRKGRP RKGSKTRQHQ REVHFMKRLP RGHHTTEQSL RFEFLNYPPF TRSLRGSQRT WAPEPR
    包装清单:
    产品编号 产品名称 包装
    LM6083-5μg Recombinant Murine FGF-8 5μg
    LM6083-25μg Recombinant Murine FGF-8 25μg
    LM6083-100μg Recombinant Murine FGF-8 100μg
    LM6083-1mg Recombinant Murine FGF-8 1mg
    - 说明书 1
    保存条件:
           -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
    注意事项:
           由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
           本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
           为了您的安全和健康,请穿实验服并戴一次性手套操作。


     

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