Recombinant Murine GM-CSF

Recombinant Murine GM-CSF

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  • ¥464
  • 联迈生物
  • LM6006-5μg
  • 中国/上海
  • 2025年07月15日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 英文名

      Recombinant Murine GM-CSF

    • 保质期

      一年

    • 供应商

      上海联迈生物工程有限公司

    • 保存条件

      -20℃或更低温度保存

    • 规格

      5μg

    Recombinant Murine GM-CSF
    产品编号 产品名称 产品包装 产品价格
    LM6006-5μg Recombinant Murine GM-CSF 5μg 464.00
     
    Species Gene ID Accession Source Length MW Tag
    Mouse 12981 LM01587 E. coli 124aa 14.1kDa
     
    About this Antibody
    Name Recombinant Murine GM-CSF (Recombinant Murine Granulocyte-Macrophage Colony Stimulating Factor; rMuGM-CSF)Recombinant Mouse GM-CSF ; 重组小鼠粒细胞巨噬细胞集落刺激因子
    Synonyms CSF2; colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; GM-CSF; GMCSFgranulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; Molgramostin; molgramostin; sargramostim; Sargramostim
    Purity >98% by SDS-PAGE and HPLC analyses.
    Biological Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine FDC-P1 cells is less than 0.05ng/ml, corresponding to a specific activity of >2.0×107IU/mg.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Formulation Lyophilized from a 0.2μm filtered solution in PBS, pH7.4.
    Endotoxin Less than 1EU/μg of rMuGM-CSF as determined by LAL method.
    Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
    Category Cytokine
    Background Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is secreted by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimulation. It was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors and has functions of stimulates the growth and differentiation of hematopoietic precursor cells from various lineages. GM-CSF has also been reported to have a functional role on non-hematopoietic cells and can induce human endothelial cells to migrate and proliferate. Additionally, it can stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. Mouse GM-CSF shares 54% sequences identity with human GM-CSF, but has no biological effects across species. GM-CSF is used as a medication to stimulate the production of white blood cells following chemotherapy and has also recently been evaluated in clinical trials for its potential as a vaccine adjuvant in HIV-infected patients.
    Amino Acid Sequence APTRSPITVT RPWKHVEAIK EALNLLDDMP VTLNEEVEVV SNEFSFKKLT CVQTRLKIFE QGLRGNFTKL KGALNMTASY YQTYCPPTPE TDCETQVTTY ADFIDSLKTF LTDIPFECKK PGQK
    包装清单:
    产品编号 产品名称 包装
    LM6006-5μg Recombinant Murine GM-CSF 5μg
    LM6006-20μg Recombinant Murine GM-CSF 20μg
    LM6006-100μg Recombinant Murine GM-CSF 100μg
    LM6006-1mg Recombinant Murine GM-CSF 1mg
    - 说明书 1
    保存条件:
           -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
    注意事项:
           由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
           本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
           为了您的安全和健康,请穿实验服并戴一次性手套操作。


     

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