- $797.50
- Abbexa
- 详见说明书
- abx151736
- 英国
- 2025年07月15日
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- 详细信息
- 文献和实验
- 技术资料
- 样本：
血清、血浆、尿液、组织、上清液等
- 库存：
60
- 标记物：
见官方网站
- 适应物种：
Human
- 应用：
ELISA
- 检测方法：
酶联免疫方法
- 检测范围：
详见说明书
- 供应商：
上海泽叶生物科技有限公司
- 规格：
96 tests
Human Growth Factor Receptor Bound Protein 2 (Grb2) ELISA Kit
Human GRB2 ELISA Kit is a sandwich ELISA kit for use with Tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Growth Factor Receptor Bound Protein 2 (GRB2)No significant cross-reactivity or interference between Growth Factor Receptor Bound Protein 2 (GRB2) and analogues was observed.
Please note that this kit is also available as a CLIA Kit abx493739.
| Target | Growth Factor Receptor Bound Protein 2 |
| Reactivity | Human |
| Tested Applications | ELISA |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.055 ng/ml |
| Validity | The validity for this kit is 6 months. |
| Storage | Store at 2°C to 8°C upon receipt. |
| Stability | The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
| Standard Form | Lyophilized |
| ELISA Type | Sandwich |
| ELISA Data | Quantitative |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Note | This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit.If you require a specific range, please contact us in advance or write your request in your order comments. |
abbexa位于世界著名的剑桥科技园区，在剑桥、英国。我们是生命科学、药物开发和生物技术部门的生物工具供应商。我们向科学界提供初级抗体、次级抗体、蛋白质、ELISA试剂盒和酶以及其他用于研究的试剂盒和工具。我们与世界各地的实验室合作，致力于为生物医学研究市场开发相关的、高质量的、经过测试的产品。
abbexa是一个专用的全球供应商和供应商的抗体蛋白。无论你是进行学术研究，药物研究，疾病研究或其他生物研究，我们的单克隆抗体，多克隆抗体，蛋白质和生物试剂的目的是为了便于您的研究。我们认识到，有时很难找到合适的抗体来满足您的需求，因此我们提供一种定制的蛋白质、肽和抗体生产管道。
官方网站：www.abbexa.com
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文献和实验Grb2蛋白(growth factor receptor-bound protein 2)
Grb2是生长因子受体结合蛋白2,又叫Ash蛋白。该蛋白参与细胞内各种受体激活后的下游调节。它能够直接与激活的表皮生长因子受体磷酸化的酪氨酸结合,参与EGF受体介导的信号转导,也能通过与Shc磷酸化的酪氨酸结合间接参与由胰岛素受体介导的信号转导。Grb2能够同时与Shc、Sos结合形成Shc-Grb2-Sos复合物,并将Sos激活，激活的Sos与质膜上的Ras蛋白结合，并将其激活,引起信号级联反应。Grb2蛋白含有一个SH2结构域和两个SH3结构域,属SH蛋白。
MicroRNA Regulation of Growth Factor Receptor Signaling in Human Cancer Cells
Aberrant expression of the epidermal growth factor receptor (EGFR) and/or human epidermal growth factor receptor 2 (HER2) is a feature of many human tumors and is associated with disease progression, treatment resistance, and poor prognosis
Regulator of Epidermal Growth Factor Signaling: Sprouty
Sprouty was first discovered through its downregulatory effect on fibroblast growth factor (FGF) receptor pathway during tracheal development. Sprouty expression is also induced by the epidermal growth factor receptor (EGFR) cascade
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