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- 详细信息
- 技术资料
- 库存:
878
- 英文名:
Recombinant Human Triggering Receptor Expressed on Myeloid Cells-Like Protein 1
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产供应北京重组人髓细胞触发受体样蛋白1(TREML1)促销,我公司销*(代"售")全品类的分子生物学试剂,价格优惠,欢迎广大科研工作者垂询订购。
名称:北京重组人髓细胞触发受体样蛋白1(TREML1)促销
英文名:Recombinant Human Triggering Receptor Expressed on Myeloid Cells-Like Protein 1
产地:国产|进口
品牌:百奥莱博
规格:10μg|50μg|500μg|1mg
编号:JN1129
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln16-Pro162在C端带有Fc标签。
TREML1质量控制:>95%(还原性SDS-PAGE)
TREML1制剂:冻干品
TREML1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
TREML1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于TREML1:
Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic vesicles in resting platelets. TREML1 be transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis. The phosphorylated TREML1 can interact with PTPN6 and PTPN11. TREML1 may participate in maintaining vascular hemostasis and regulating coagulation and inflammation at sites of injury.
北京重组人髓细胞触发受体样蛋白1(TREML1)促销正在火爆热销,除此之外,为您推荐下别热销产品:
·重组人LAIR1(白细胞相关免疫球蛋白样受体1)
编号:JN1678
英文名称:Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln22-His163在C端含有His标签。
LAIR1质量控制:>95%(还原性SDS-PAGE)
LAIR1制剂:冻干品
LAIR1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
LAIR1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于LAIR1:
Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear cells, including natural killer (NK) cells, T-cells, B-cells, monocytes, and dendritic cells, highly in naive T-cells and B-cells. As an inhibitory receptor, LAIR1 plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. LAIR1 plays inhibitory role independently of SH2-containing phosphatases and modulates cytokine production in CD4+ T-cells. It down-regulates IL2 and IFNG production while inducing secretion of transforming growth factor beta, also down-regulates IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion. LAIR1 inhibits the differentiation of peripheral blood precursors towards dendritic cells. It also restrains proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells.
北京重组人髓细胞触发受体样蛋白1(TREML1)促销关键词:重组人髓细胞触发受体样蛋白1蛋白,重组人TREML1,重组髓细胞触发受体样蛋白1,JN1129
·重组小鼠白介素IL-11(白细胞介素11)
编号:JN0405
英文名称:Recombinant Mouse Interleukin-11
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备,目的基因编码的Pro22-Leu199在C端含有His标签。
IL-11质量控制:>95%(还原性SDS-PAGE)。
IL-11制剂:冻干品
IL-11保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
IL-11复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于IL-11:
Interleukin-11(IL-11) is a secreted protein and belongs to the IL-6 superfamily. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induceacute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cellproliferation and differentiation and could be use as a therapeutic for osteoporosis. IL-11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. In addition to having lymphopoietic/hematopoietic and osteotrophic properties, it has functions in many other tissues, including the brain, gut, testis and bone.
北京重组人髓细胞触发受体样蛋白1(TREML1)促销关键词:重组人髓细胞触发受体样蛋白1蛋白,重组人TREML1,重组髓细胞触发受体样蛋白1,JN1129
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我公司生产供应销*(代"售")的重组蛋白产品正全系列现货促销,满分期待您的垂询选购北京重组人髓细胞触发受体样蛋白1(TREML1)促销。
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