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北京现货JN1420型重组小鼠TIGIT库存

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  • ¥130 - 2030
  • 百奥莱博
  • JN1420-NXF
  • 北京
  • 2025年07月12日
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    • 详细信息
    • 技术资料
    • 库存

      710

    • 英文名

      Recombinant Mouse T cell Immunoreceptor with Ig and ITIM domains

    • 保质期

      长期

    • 供应商

      北京百奥莱博科技有限公司

    • 保存条件

      冻干蛋白置于-20℃

    特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。

    北京现货JN1420型重组小鼠TIGIT库存由专业试剂供应商北京百奥莱博提供,用于生化研究,本产品质量好,且极具价格优势,深为用户称道,了解更多重组小鼠TIGIT等重组蛋白产品请联*(代"系")我司咨询订购。


    名称:北京现货JN1420型重组小鼠TIGIT库存
    规格:10μg|50μg|500μg|1mg
    品牌:百奥莱博
    英文名:Recombinant Mouse T cell Immunoreceptor with Ig and ITIM domains
    本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gly26-Phe135在C端含有His标签。

    TIGIT 质量控制:>95%(还原性SDS-PAGE)

    TIGIT 制剂:冻干品

    TIGIT 保存
    冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

    TIGIT 复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    冻干蛋白请溶于ddH2O。
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于TIGIT
    T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called WUCAM, VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM), and is expressed on regulatory, memory, activated T cells and NK cells. TIGIT binds to CD155(PVR) that appear on dendritic cells (DC), macrophages and endothelium with high affinity, and CD112(PVRL2) with lower affinity, but not CD113 (PVRL3). TIGIT-Fc fusion protein could interact with PVR on DC and enhance the secretion of IL-10, but inhibit the macrophage activation. Mice lacking TIGIT show increased T cell responses and susceptibility to autoimmune challenges, while knockdown of TIGIT with siRNA in human memory T cells did not affect T cell responses.

    关于北京现货JN1420型重组小鼠TIGIT库存的更详细说明,请致电我公司咨询,我们将以最饱满的热情为您提供解答,此外,我公司专业供应下列产品:

    ·重组人β-NGF(β神经生长因子)
    编号:JN0261
    英文名称:Recombinant Human beta-Nerve Growth Factor
    规格:10μg|50μg|500μg|1mg
    本品由我们的哺乳动物表达系统制备,目的基因编码的Ser122-Arg239表达纯化而来。

    beta-NGF质量控制:>95%(还原性SDS-PAGE)。

    beta-NGF制剂:冻干品

    beta-NGF保存
    冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天。
    复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。

    beta-NGF复溶
    1、试剂开盖前请先离心。
    2、复溶浓度应大于100 μg/ml.
    3、冻干蛋白溶于ddH2O中
    4、复溶后根据使用量分装保存,避免反复冻融。

    关于beta-NGF
    Human β-Nerve Growth Factor (β-NGF) was initially isolated in the mouse submandibular gland. It is composed of three non-covalently linked subunits α, β, and γ; it exhibits all the biological activities ascribed to NGF. It is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. Β-NGF is a neurotrophic factor that signals through its receptor β-NGF, and plays a crucial role in the development and preservation of the sensory and symp*(代"a")thetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. These results suggest that β-NGF is a pleiotropic cytokine, which in addition to its neurotropic activities may have an important role in the regulation of the immune system. Human β-NGF shares 90% sequence similarity with mouse protein and shows cross-species reactivity.


    北京现货JN1420型重组小鼠TIGIT库存关键词:Recombinant Mouse T cell Immunoreceptor with Ig an,JN1420,重组小鼠TIGIT蛋白,百奥莱博,重组TIGIT


    ·重组人T细胞免疫球蛋白黏蛋白3(TIM-3)(HAVCR2)
    编号:JN1157
    英文名称:Recombinant Human T cell Immunoglobulin and Mucin Domain-3
    规格:10μg|50μg|500μg|1mg
    本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser22-Arg200在C端含有Fc标签和His标签

    TIM-3质量控制:>95%(还原性SDS-PAGE)

    TIM-3制剂:冻干品

    TIM-3保存
    冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

    TIM-3复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    冻干蛋白请溶于ddH2O。
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于TIM-3
    Hepatitis A virus cellular receptor 2(HAVCR2)is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein belongs to the immunoglobulin superfamily, and TIM family of proteins. The protein regulates macrophage activation. It inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and it is receptor for LGALS9. CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.


    北京现货JN1420型重组小鼠TIGIT库存关键词:Recombinant Mouse T cell Immunoreceptor with Ig an,JN1420,重组小鼠TIGIT蛋白,百奥莱博,重组TIGIT

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    北京百莱博科技有限公司是重组蛋白产品的专业生产供应销*(代"售")商,恭候您的咨询选购北京现货JN1420型重组小鼠TIGIT库存

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