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- 详细信息
- 技术资料
- 库存:
610
- 英文名:
Recombinant Human Signal Transducer and Activator of Transcription 5B
- 保质期:
6个月
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
收到货后请置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人信号转导与转录激活因子5B(STAT5B)怎么卖,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人信号转导与转录激活因子5B(STAT5B)
编号:JN0882
产地:国产|进口
品牌:百奥莱博
英文名:Recombinant Human Signal Transducer and Activator of Transcription 5B
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Thr321在C端含有His标签。
STAT5B质量控制:>95%(还原性SDS-PAGE)
STAT5B制剂:液体
STAT5B保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于STAT5B:
Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible for an array of cellular activities including regulating growth, survival, differentiation, motility, and the immune response. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. Signal transduction and activator of transcription 5 (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL22, IL6). STAT5 has two isoforms (A and B) that share 93% amino acid identity and bind the DNA consensus site TTCN3GAA. STAT5 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, translocates to the nucleus and activates transcription of specific genes. STAT5 is involved in a wide array of biological processes ranging from regulating apoptosis to adult mammary gland proliferation, differentiation and survival.
关键词:重组人信号转导与转录激活因子5B蛋白,JN0882,重组人STAT5B,重组信号转导与转录激活因子5B
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