重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)库存在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)库存
编号：JN1377
品牌：百奥莱博
产地：国产|进口
英文名：Recombinant Mouse Programmed Cell Death 1 Ligand 1
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Phe19-Thr238在C端带有Fc标签。

CD274/PD-L1/B7-H1质量控制：＞95%(还原性SDS-PAGE)

CD274/PD-L1/B7-H1制剂：冻干品

CD274/PD-L1/B7-H1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD274/PD-L1/B7-H1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD274/PD-L1/B7-H1：
Mouse Programmed cell death 1 ligand 1(Cd274,PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.B7-H1 has been identified as one of two ligands for programmed death1 (PD1), a member of the CD28 family of immunoreceptors. B7-H1 is constitutively expressed in several organs such as heart, skeletal muscle B7-H1 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. The costimulatory function of B7-H1 is critical for enhancing maturation and differentiation of T-cells in lymphoid organs.B7-H1 expression is also induced in dendritic cells and keratinocytes after IFN gamma stimulation. Interaction of B7-H1 with PD1 results in inhibition of TCR-mediated proliferation and cytokine production. The B7-H1:PD1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.


关于重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)库存的更详细说明，请致电我公司咨询，我们将以最饱满的热情为您提供解答，此外，我公司专业供应下列产品：
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重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)库存关键词：重组小鼠B7-H1,C端带Fc标签,JN1377,重组小鼠PD-L1,重组小鼠CD274


·重组人CLEC10A
编号：JN1853
英文名称：Recombinant Human C-Type Lectin Domain Family 10 Member A
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln61-His316在C端含有His标签。

CLEC10A质量控制：＞95%(还原性SDS-PAGE)

CLEC10A制剂：冻干品

CLEC10A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CLEC10A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CLEC10A：
C-Type Lectin Domain Family 10 Member A (CLEC10A) is a type II transmembrane C-type lectin that is expressed on immature myleloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10A/MGL binds and internalizes molecules with terminal nonsialylated GalNAc carbohydrates such as the Tn carcinoma antigen. CLEC10A/MGL also binds the GP envelope glycoprotein on Marburg and Ebola viruses and enhances viral entry and infectivity. It constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. CLEC10A is thought to participate in the recognition of molecules from both altered self and pathogens due to its monosaccharide specificity for Gal and N-acetylgalactosamine (GalNAc). Human and rat carry a single gene for CLEC10A/MGL, while mouse has two closely related MGL1 and MGL2 genes.


重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)库存关键词：重组小鼠B7-H1,C端带Fc标签,JN1377,重组小鼠PD-L1,重组小鼠CD274

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我公司生产供应销*(代"售")的重组蛋白产品正全系列现货促销，满分期待您的垂询选购重组小鼠CD274(PD-L1)(B7-H1)(C端带Fc标签)库存。