重组小鼠IL-36b(IL-1F8)供应

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组小鼠IL-36b(IL-1F8)供应在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组小鼠IL-36b(IL-1F8)供应
品牌：百奥莱博
英文名：Recombinant Mouse Interleukin-36 beta
编号：JN1398
产地：国产|进口
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ser31-Lys183表达纯化得来。

IL-36b/IL-1F8质量控制：＞95%(还原性SDS-PAGE)

IL-36b/IL-1F8制剂：冻干品

IL-36b/IL-1F8保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IL-36b/IL-1F8复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IL-36b/IL-1F8：
Mouse Interleukin 36 beta (IL-36B)is a member of the IL-1 family of proteins. It is a cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. IL-36B is synthesized in several cells including resting and activated monocytes, and B cells. The receptor for IL-36 beta is thought to be a combination of IL-1 Rrp2 and IL-1 RAcP. Interleukin 36 beta is one part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP. Interleukin 36 beta are involved in a number of fundamental biological processes such as stimulating production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes, inducing expression of a number of antimicrobial peptides including beta-defensin 4 and beta-defensin 103 as well as a number of matrix metalloproteases , inducing the production of proinflammatory cytokines in bone marrow-derived dendritic cells (BMDCs), including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23, and activating p38 MAPK phosphorylation in BMDCs.Moreover, interleukin 36 beta may be involved in skin inflammatory response by acting on keratinocytes, dendritic cells, and indirectly on T cells to drive tissue infiltration, cell maturation and cell proliferation. It plays an important role in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II and inducing the production of IFN-gamma, IL-4 and IL-17 by T helper 1 (Th1) cells, cultured CD4+ T cells and splenocytes.

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重组小鼠IL-36b(IL-1F8)供应关键词：重组小鼠IL-36b蛋白,JN1398,重组小鼠IL-1F8,重组IL-36b


·重组人白介素22受体α2(带Fc标签)
编号：JN0402
英文名称：Recombinant Human Interleukin-22 receptor subunit alpha-2/Interleukin-22 Binding Protein
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Thr22-Pro231在N端含有Fc标签。

IL-22RA2质量控制：＞95%(还原性SDS-PAGE)。

IL-22RA2制剂：冻干品

IL-22RA2保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-22RA2复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-22RA2：
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.


重组小鼠IL-36b(IL-1F8)供应关键词：重组小鼠IL-36b蛋白,JN1398,重组小鼠IL-1F8,重组IL-36b

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我公司正在优惠促销重组蛋白等系列产品，期待您的咨询选购重组小鼠IL-36b(IL-1F8)供应。