重组小鼠ULBP-1现货供应

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")重组小鼠ULBP-1现货供应，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组小鼠ULBP-1现货供应
产地：国产|进口
规格：10μg|50μg|500μg|1mg
编号：JN1375
英文名：Recombinant Mouse UL16 Binding Protein-1/NKG2D ligand 1
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Pro26-Thr211在C端含有His标签。

ULBP-1质量控制：＞95%(还原性SDS-PAGE)

ULBP-1制剂：冻干品

ULBP-1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ULBP-1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ULBP-1：
Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocomp*(代"a")tibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. It can activate multiple signaling pathways in primary NK cells, gamma delta T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines.ULBP1 is expressed in wide range of tissues including heart, brain, lung, liver, bone marrow and some tumor cells, T-cells, B-cells, As an unconventional member of the MHC class I family, ULBP1 is able to interact with soluble CMV glycoprotein UL16 in CMV infected cells. The interaction with UL16 blocked the interaction with the NKG2D receptor, and thus might escape the immune surveillance. Furthermore, UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. The ULBP1 regulation may have implications for development of new therapeutic strategies against cancer cells.

重组小鼠ULBP-1现货供应极具性价比，此外，我公司正火爆促销以下产品：
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SDS-PAGE蛋白质次高分子标准 UAO
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王树脂 β-carotene
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重组小鼠ULBP-1现货供应关键词：重组小鼠ULBP-1蛋白,JN1375,重组ULBP-1,Recombinant Mouse UL16 Binding Protein-1,百奥莱博


·重组小鼠颗粒酶D(Granzyme D)
编号：JN1530
英文名称：Recombinant Mouse Granzyme D
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ile21-Leu252在C端含有His标签。

Granzyme D质量控制：＞95%(还原性SDS-PAGE)

Granzyme D制剂：冻干品

Granzyme D保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Granzyme D复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Granzyme D：
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a role in stromal cell-lymphocyte interactions.


重组小鼠ULBP-1现货供应关键词：重组小鼠ULBP-1蛋白,JN1375,重组ULBP-1,Recombinant Mouse UL16 Binding Protein-1,百奥莱博

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