JN0488型重组人OX40(TNFRSF4)(CD134)

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博供应的JN0488型重组人OX40(TNFRSF4)(CD134)(C端Fc标签)批发用于科研目的生化试验项目，本产品质量好，且极具价格优势，深为用户称道，了解更多重组人OX40(TNFRSF4)(CD134)(C端Fc标签)等重组蛋白产品请联*(代"系")我司咨询订购。

名称：JN0488型重组人OX40(TNFRSF4)(CD134)(C端Fc标签)批发
编号：JN0488
英文名：Recombinant Human OX40L receptor
品牌：百奥莱博
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu29-Ala216在C端带有Fc标签。

OX40/TNFRSF4/CD134质量控制：＞95%(还原性SDS-PAGE)

OX40/TNFRSF4/CD134制剂：冻干品

OX40/TNFRSF4/CD134保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

OX40/TNFRSF4/CD134复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于OX40/TNFRSF4/CD134：
OX40,also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.

除JN0488型重组人OX40(TNFRSF4)(CD134)(C端Fc标签)批发外，我公司正在打折促销以下产品：

·重组人白介素IL-25(白细胞介素25)
编号：JN0407
英文名称：Recombinant Human Interleukin-25
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Tyr33-Gly177在C端含有His标签。

IL-25质量控制：＞95%(还原性SDS-PAGE)。

IL-25制剂：冻干品

IL-25保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-25复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-25：
Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Human interleukin-17E (IL17E), also referred to as Interleukin-25 (IL25), is a distinct member of the IL17 cytokine family comprised of at least six members sharing a conserved cysteine-knot structure but divergent at the N-terminus. IL25 is a glycoprotein secreted as dimers by innate effector eosinophils and basophils, and present at very low levels in various peripheral tissues. IL25, together with IL17B, are ligands for the cytokine receptor IL17BR, and the cross-linking induces NF-κB activation and production of the proinflammatory chemokine IL-8, as well as ERK, JNK, and p38 activation. Overexpression of IL25 gene in transgenic mice suggested that this cytokine can regulate hematopoietic and immune functions, and additionally is identified as a proinflammatory cytokine favoring Th2-type immune responses possibly by enhancing the maintenance and functions of adaptive Th2 memory cells.


JN0488型重组人OX40(TNFRSF4)(CD134)(C端Fc标签)批发关键词：JN0488,C端Fc标签,重组人CD134,重组人OX40,重组人TNFRSF4


·重组人白介素IL-12(白细胞介素12)
编号：JN0399
英文名称：Recombinant Human Interleukin-12
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Arg23-Ser219&Ile23-Ser328表达纯化而来。

IL-12质量控制：＞95%(还原性SDS-PAGE)。

IL-12制剂：冻干品

IL-12保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

IL-12复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于IL-12：
IL-12 is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit.Human and mouse IL‑12 share 70% and 60% amino acid sequence identity in their p40 and p35 subunits, respectively. IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-γ. T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.


JN0488型重组人OX40(TNFRSF4)(CD134)(C端Fc标签)批发关键词：JN0488,C端Fc标签,重组人CD134,重组人OX40,重组人TNFRSF4

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我公司正在打折促销重组蛋白全系列产品，恭候您的咨询选购JN0488型重组人OX40(TNFRSF4)(CD134)(C端Fc标签)批发。