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- 详细信息
- 技术资料
- 库存:
670
- 英文名:
Recombinant Human Programmed Cell Death 1 Ligand 1
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冻干蛋白置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人PD-L1(B7-H1)厂家现货,我公司供应的分子生物学试剂品类齐全,且具有优势价格,欢迎新老客户垂询订购。
名称:重组人PD-L1(B7-H1)厂家现货
英文名:Recombinant Human Programmed Cell Death 1 Ligand 1
规格:10μg|50μg|500μg|1mg
编号:JN1462
品牌:百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe19-Thr239在C端带mFc标签。
PD-L1/B7-H1质量控制:>95%(还原性SDS-PAGE)
PD-L1/B7-H1制剂:冻干品
PD-L1/B7-H1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
PD-L1/B7-H1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于PD-L1/B7-H1:
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
我公司的重组人PD-L1(B7-H1)厂家现货,性价比高,货期短,送货上门,欢迎您来电咨询购买,另外,我公司还生产供应销*(代"售")下列产品:
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ARB13065 小鼠乳铁传递蛋白/乳铁蛋白(LF/LTF)免费代测 Mouse lactoferrin,ltf/lf ELISA KIT
乳糖醇 L(+)-Rhamnose monohydrate 585-86-4
4-羟基吡*(代"啶") Maltotetraose 626-64-2
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IEF阴极缓冲液 20× 250ml|500ml
6104-58-1 Coomassie brilliant blue G-250 考马斯亮蓝
2′-脱氧尿苷-5′-单磷酸二*盐 Farnesol 42155-08-8
ARB11526 人胶原凝集素(Collectin)含量分析 Human Collectin ELISA KIT
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BL1230 2×HEPES(PH7.2-7.4,无菌)
重组人PD-L1(B7-H1)厂家现货关键词:JN1462,重组人PD-L1,重组人PD-L1蛋白,重组人B7-H1,重组PD-L1
·重组人神经调节蛋白1β(N端带His标签)(NRG1)
编号:JN1224
英文名称:Recombinant Human Neuregulin-1 beta
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Lys246在N端含有His标签。
NRG1质量控制:>95%(还原性SDS-PAGE)
NRG1制剂:冻干品
NRG1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
NRG1复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于NRG1:
neuregulin-1 (heregulin-1,NRG1) is a member ofneuregulin family, which is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. NRG1 isoforms can be classified into type I, type II and type III isoforms. NRG1 directs ligand for ERBB3 and ERBB4 tyrosine kinase receptors, concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.
重组人PD-L1(B7-H1)厂家现货关键词:JN1462,重组人PD-L1,重组人PD-L1蛋白,重组人B7-H1,重组PD-L1
·重组小鼠脊灰病毒受体(PVR)(CD155)
编号:JN1620
英文名称:Recombinant Mouse Poliovirus Receptor
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Asp29-Leu348在C端含有His标签。
PVR/CD155质量控制:>95%(还原性SDS-PAGE)
PVR/CD155制剂:冻干品
PVR/CD155保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
PVR/CD155复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于PVR/CD155:
Mouse poliovirus receptor (PVR, CD155) is a type I transmembrane (TM) glycoprotein that is a member of the nectin-related family of adhesion proteins within the immunoglobulin superfamily. It binds other molecules including vitronectin, Nectin3, DNAM1, CD96, and TIGIT, but does not bind homotypically. CD155 includes a 28 aa signal sequence, a 318 aa extracellular domain (ECD) with one N-terminal V-type and two C2-type Ig-like domains, a 24 aa TM segment and a 38 aa cytoplasmic tail. Epithelial, endothelial, and many immune cells show low CD155 expression. It is up-regulated on endothelia by IFNγ, and is highly expressed on immature thymocytes, lymph node dendritic cells, and tumor cells of epithelial and neuronal origin. On migrating cells, it is concentrated at the leading edge, where it binds basement membrane vitronectin, recruits Nectin-3-expressing cells, and cooperates with PDGF and integrin αvβ3 to promote cell migration. Binding of monocyte DNAM-1 to endothelial cell CD155 promotes transendothelial migration. Enhanced CD155 expression in tumor cells contributes to loss of contact inhibition and increased migration, but also allows tumor cell recognition and killing by DNAM-1or CD96 expressing NK cells.
我公司生产供应销*(代"售")的重组蛋白产品正全系列现货促销,满分期待您的垂询选购重组人PD-L1(B7-H1)厂家现货。
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