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- 详细信息
- 技术资料
- 库存:
530
- 英文名:
Recombinant Human Caspase-10
- 保质期:
6个月
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
收到货后请置于-20℃
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括北京现货重组人Caspase-10(CASP10)库存在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:北京现货重组人Caspase-10(CASP10)库存
规格:10μg|50μg|500μg|1mg
产地:国产|进口
品牌:百奥莱博
编号:JN1004
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Val220-Ile480在C端含有His标签。
CASP10质量控制:>95%(还原性SDS-PAGE)
CASP10制剂:液体
CASP10保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于CASP10:
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7). CASP10 cleaves and activates caspases 3 and 7, but itself is processed by caspase 8. Defects in CASP10 are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
除北京现货重组人Caspase-10(CASP10)库存外,我公司正在打折促销以下产品:
·重组小鼠IgG1-Fc
编号:JN1161
英文名称:Recombinant Mouse Immunoglobulin G1 Fc
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Pro99-Lys324表达纯化得来。
IgG1-Fc质量控制:>95%(还原性SDS-PAGE)
IgG1-Fc制剂:冻干品
IGHG1保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
IgG1-Fc复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于IgG1-Fc:
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.
北京现货重组人Caspase-10(CASP10)库存关键词:重组人CASP10,重组人Caspase-10,重组人Caspase-10蛋白,重组Caspase-10,JN1004
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17372-87-1 伊红Y(水溶) Eosin Y
北京现货重组人Caspase-10(CASP10)库存关键词:重组人CASP10,重组人Caspase-10,重组人Caspase-10蛋白,重组Caspase-10,JN1004
·重组小鼠催乳素受体(PRLR)(C端带His标签)
编号:JN1507
英文名称:Recombinant Mouse Prolactin receptor
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln20-Asp229在C端含有His标签。
Prolactin R 质量控制:>95%(还原性SDS-PAGE)
Prolactin R 制剂:冻干品
Prolactin R 保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Prolactin R 复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Prolactin R :
The prolactin receptor (PRLR) is a member of the class I cytokine/lactogen receptor family which mediates the diverse cellular actions of prolactin in several tissues. PRLRs are expressed in normal and neoplastic human breast tissue, and in most breast cancer cells. PRLR contains an extracellular region that binds prolactin, a transmembrane region, and a cytoplasmatic region required for the activation of the Jak2–Stat5 signal transduction pathway by Prl which is essential for transcriptional activation of all known prolactin regulated genes. PRLRs have also been observed in ovarian follicular cells of mice, pigs, sheep, deer, and humans, as well as in luteal tissue in cow and horse ovaries. Furthermore, PRLR knockout mice exhibit failure of embryonic implantation, reduced number of mature oocytes, and low fertilization rates. Knockout females also display a reduced number of primary follicles.
我公司生产供应销*(代"售")的重组蛋白产品正全系列现货促销,满分期待您的垂询选购北京现货重组人Caspase-10(CASP10)库存。
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