重组人S100A12(S100钙结合蛋白A12)厂家

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖重组人S100A12(S100*结合蛋白A12)厂家在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：重组人S100A12(S100*结合蛋白A12)厂家
规格：10μg|50μg|500μg|1mg
编号：JN1298
产地：国产|进口
英文名：Recombinant Human S100 calcium-binding protein A12
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Glu92表达纯化得来。

S100A12质量控制：＞95%(还原性SDS-PAGE)

S100A12制剂：冻干品

S100A12保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

S100A12复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于S100A12：
Human EN-RAGE belongs to the S100/calgranulin superfamily. There are at least 21 different S100 proteins and the protein is 100% soluble in ammonium sulfate at neutral pH. S100 proteins play a role in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.Human EN-RAGE is characterized by two EF-hand calcium-binding motifs, zinc- and copper-binding protein.S100A12 is a disulfide-linked homodimer and the interface between the two subunits is composed mostly of hydrophobic residues.Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. EN-RAGE acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. It also acts as a monocyte and mast cell chemoattractant. Moreover, it can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation. It can inhibit the activity of matrix metalloproteinases; MMP2, MMP3 and MMP9 by chelating Zn2+from their active sites.

除重组人S100A12(S100*结合蛋白A12)厂家外，我公司正在打折促销以下产品：

·重组人ULBP-2(UL16结合蛋白2)
编号：JN1140
英文名称：Recombinant Human UL16 Binding Protein-2/NKG2D ligand 2
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly26-Ser217在C端带有Fc标签。

ULBP-2质量控制：＞95%(还原性SDS-PAGE)

ULBP-2制剂：冻干品

ULBP-2保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ULBP-2复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ULBP-2：
NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance.


重组人S100A12(S100*结合蛋白A12)厂家关键词：JN1298,重组人S100A12,重组人S100A12蛋白,重组人S100*结合蛋白A12,重组S100A12


·重组小鼠GDF15(生长分化因子15)
编号：JN1313
英文名称：Recombinant Mouse Growth differentiation factor 15
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Trp31-Ala303在C端含有His标签。

GDF15质量控制：＞95%(还原性SDS-PAGE)

GDF15制剂：冻干品

GDF15保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

GDF15复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于GDF15：
Growth differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes.GDF15 is most abundant in the liver. Its expression in liver can be considerably up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF-15 promotes proliferation or growth arrest and differentiation due to differences in cellular differentiation. GDF15 prevents apoptosis in cerebellar granule neurons by activating Akt and inhibiting endogenously active ERK. GDF15 is a novel autocrine/endo*(代"c")rine factor that antagonizes the hypertrophic response and loss of ventricular performance.


重组人S100A12(S100*结合蛋白A12)厂家关键词：JN1298,重组人S100A12,重组人S100A12蛋白,重组人S100*结合蛋白A12,重组S100A12

9007-34-5 胶原蛋白Ⅱ型 Collagen TypeⅡ
Na-*甲酰-L-精*酸乙酯盐*(代"酸")盐 DEAE Cellulose 2645-08-1
B0401 标准新生牛血清(辐照灭菌)
*酚蓝水溶液  1%|2% 10ml
E0603 脱纤维裂解山羊血(无菌)
ARB12255 大鼠血管紧张素转化酶(ACE)酶免分析 Rat angiotensin converting enzyme,ace ELISA KIT
BL0929 RBITC标记羊抗马IgG抗体
ARB13682 兔血管生成素2(ANG-2)免费代测 Rabbit angiopoietin 2,ang-2 ELISA KIT
BTN3660 非冻型组织DNA保存液 Tissue DNALOCKER
D(-)樟脑磺酸 DL-Glyceraldehyde 3144-16-9
ARB14211 鹅白细胞介素12(IL-12)血清中含量检测 
硬脂酸* L-Arginine methyl ester dihydrochloride 593-29-3

我公司生产供应销*(代"售")的重组蛋白产品正全系列现货促销，满分期待您的垂询选购重组人S100A12(S100*结合蛋白A12)厂家。