重组牛痘病毒可溶性干扰素α/β受体B18促销

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产供应重组牛痘病毒可溶性干扰素α/β受体B18促销，我公司销*(代"售")全品类的分子生物学试剂，价格优惠，欢迎广大科研工作者垂询订购。

名称：重组牛痘病毒可溶性干扰素α/β受体B18促销
编号：JN1484
品牌：百奥莱博
英文名：Recombinant Vacciniavirus Soluble interferon alpha/beta receptor B18
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的His20-Glu351在C端含有His标签。

B18R质量控制：＞95%(还原性SDS-PAGE)

B18R制剂：冻干品

B18R保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

B18R复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于B18R：
B18R, also known as B19R in the Copenhagen strain of Vaccinia, is a type I interferon (IFN)-binding protein encoded by the B18R open reading frame in the Western Reserve strain of vaccinia virus. B18R exists in two forms, soluble and membrane-bound form and also has a broad species specificity. B18R has high affinity for human IFN-alpha and also binds rabbit, bovine, rat, pig, and mouse IFN-alpha and IFN-beta. Secreted B18R binds to uninfected and infected cells. B18R presents at the cell surface and protects cells from the antiviral state. It has shown that binding of soluble recombinant B18R protects cultured cells from IFN and allows vaccinia virus replication.

除重组牛痘病毒可溶性干扰素α/β受体B18促销外，我公司正在打折促销以下产品：

·重组人B型*尿肽(NPPB)
编号：JN1946
英文名称：Recombinant Human Natriuretic Peptides B
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的His27-His134在N端含有His标签。

NPPB质量控制：＞95%(还原性SDS-PAGE)

NPPB制剂：液体

NPPB保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于NPPB：
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3.

·重组人激活转录因子1(ATF1)
编号：JN0884
英文名称：Recombinant Human Activating Transcription Factor 1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Val271在C端含有His标签。

ATF1质量控制：＞95%(还原性SDS-PAGE)

ATF1制剂：冻干品

ATF1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ATF1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ATF1：
Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. ATF1 binds the cAMP response element (CRE) (consensus: 5-GTGACGT[AC][AG]-3), a sequence present in many viral and cellular promoters. It also binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes, represses the expression of FTH1 and other antioxidant detoxification genes, triggers cell proliferation and transformation. ATF1 is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and CDK3. Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation.


重组牛痘病毒可溶性干扰素α/β受体B18促销关键词：JN1484,百奥莱博,重组牛痘病毒可溶性干扰素α/β受体B18蛋白,Recombinant Vacciniavirus Soluble interferon alpha

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重组牛痘病毒可溶性干扰素α/β受体B18促销关键词：JN1484,百奥莱博,重组牛痘病毒可溶性干扰素α/β受体B18蛋白,Recombinant Vacciniavirus Soluble interferon alpha


·重组小鼠DNAM-1(CD226)
编号：JN1618
英文名称：Recombinant Mouse DNAX Accessory Molecule-1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu19-Pro254在C端含有His标签。

DNAM-1/CD226质量控制：＞95%(还原性SDS-PAGE)

DNAM-1/CD226制剂：冻干品

DNAM-1/CD226保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

DNAM-1/CD226复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于DNAM-1/CD226：
Mouse DNAX accessory molecule-1(DNAM-1) is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily. As an activating receptor, it interacts with the ligands CD155 and CD112, and activates natural killer (NK) cells via its immu-noreceptor tyrosine-based activatory motif (ITAM). Mature mouse DNAM-1 has extracellular domain (ECD) that contains two Ig-like C2-set domains, and possesses a cytoplasmic region that contains motifs for binding PDZ domains. DNAM-1 is expressed on several lymphoid and myeloid cell types and interacts with CD155/PVR and Nectin-2/CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, induces dendritic cell maturation, initiates megakaryocyte and activated platelet adhesion to vascular endothelial cells, and stimulates monocyte extravasation; Conversely, it inhibits the formation of osteoclasts. Platelet-endothelium interactions that are mediated by DNAM-1 enable the metastasis of tumor cells to the lung.

我公司生产供应销*(代"售")的分子生物学试剂正全品类优惠促销，十分期待您的咨询选购重组牛痘病毒可溶性干扰素α/β受体B18促销。