环指蛋白17抗体价格

英文名称  Anti-RNF17 
中文名称  环指蛋白17抗体价格
别    名  Mmip 2; Mmip2; Ring finger protein 17; RNF 17; SPATA 23; SPATA23; Spermatogenesis associated 23; TDRD 4; TDRD4; Tudor domain containing 4. 
浓    度  1mg/1ml 
规 格  0.2ml/200μg
抗体来源  Rabbit  
克隆类型  polyclonal 
交叉反应  Human, Mouse, Rat, Dog, Cow, Horse, Sheep
产品类型  一抗    
研究领域  细胞生物 免疫学 染色质和核信号  
蛋白分子量  predicted molecular weight: 185kDa 
性    状  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human RNF17 
亚    型  IgG 
纯化方法  affinity purified by Protein A 
储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
产品应用   ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200 
（石蜡切片需做抗原修复） 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
产品介绍 The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF17 (ring finger protein 17) or tudor domain-containing protein 4, TDRD4, SPATA23, Mmip-2 or FLJ11045, is a testis-specific protein and and novel key regulator of spermiogenesis containing 1,623 amino acids. By distributing Mad proteins to the cytoplasm, RNF17 regulates the transcriptional activity of c-Myc. Although showing localization in the nucleus, RNF17 is predominantly observed in cytoplasm and is a component of a novel nuage found in male germ cells. The gene encoding RNF17 maps to human chromosome 13q12.12 and encodes one RING-type zinc finger and four tudor domains. As a result of alternative splice events, five RNF17 isoforms exisit.
Function : Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity). 
Subunit : Interacts with MXD1, MXD3, MXD4, MXI1 and PIWIL1. Self-associates (By similarity).
Subcellular Location : Cytoplasm (By similarity). Nucleus (By similarity). Note=Predominantly found in the cytoplasm. Component of a nuage in male germ cells (an electron-dense spherical cytoplasmic body present in late pachytene and diplotene spermatocytes and in elonging spermatids) (By similarity). 
Tissue Specificity : Testis specific. 
Similarity : Contains 1 RING-type zinc finger. 
Contains 4 Tudor domains. 
环指蛋白17抗体价格的功能
抗体的主要功能是与抗原（包括外来的和自身的）相结合，从而有效地清除侵入机体内的微生物、寄生虫等异物，抗体（antibody）是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活，也可能无效但有时也会对机体造成病理性损害，如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生，对人体可造成危害。
公司抗体应用于WB、IHC、IF、ELISA等实验中，环指蛋白17抗体价格品质保证，提供完善的售前、售中、售后服务！欢迎来电咨询或联系在线客服！我们将竭诚为您服务！
环指蛋白17抗体价格的优点：
①耐热、耐酸、耐碱、抗有机溶剂以及金属离子，稳定性好，室温下可以长期保存；
②制备简单，操作方便，可以进行批量；
③不必免疫动物，且可获得免疫动物所不能得到的“抗体”；
④可以反复使用；
⑤价格低廉。因此，设计、合成既具有类似生物抗体的高亲合性和高专一性，又具有耐热、耐酸、耐碱且又可以长期稳定的人工抗体，在部分领域替代生物抗体以进行仿生分子识别，或者完成一些生物抗体所不能完成的工作，具有重要的科学意义，在化学、生命科学和环境科学等方面具有广阔的应用前景
公司专业供应各种进口、国产一抗及二抗，品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌，品种多达7000多种，由于产品的数量众多，产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。
环指蛋白17抗体价格具有高度的特异性，免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来，以此作为抗原或半抗原，通过免疫动物后获得特异性的抗体，再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的，因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来，以其达到对组织或细胞中的未知抗原进行定性，定位或定量的研究。
环指蛋白17抗体价格包括以下几个步骤：
1、制备抗原。
2、选择实验动物。
3、动物免疫。
4、试取血进行测试，看看是否成功免疫。
5、如果成功免疫，杀死实验动物，采集全部血清。
6、纯化出抗体。
7、鉴定抗体。包括纯度以及特异性。
SREBP-1胆固醇调节元件结合蛋白1抗体规格:0.1ml
phospho-Tauprotein(Ser214)磷酸化微管相关蛋白抗体规格:0.1ml
TCTP翻译控制瘤蛋白抗体规格:0.1ml
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betaAdaptin/AP2衔接蛋白β抗体规格:0.1ml
MARCH6膜相关环指蛋白6抗体规格:0.2ml
SLC27A6/ACSVL2脂肪酸转运蛋白6抗体规格:0.2ml
phospho-CDKN1B/P27kip1(Thr198)磷酸化P27抗体/周期素依赖激酶抑制剂抗体规格:0.1ml
RAP2B原基因相关蛋白RAP2B抗体规格:0.2ml
presenilin1/PS-1早老素蛋白-1抗体规格:0.1ml
Resistin抵抗素抗体规格:0.1ml
Gastrin Releasing Peptide (1-16), human    Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro
gp38    Arg-Val-Thr-Ala-Ile-Glu-Lys-Tyr-Leu-Gln-Asp-Gln-Ala- Arg-Leu-Asn-Ser-Trp-Gly-Cys-Ala-Phe-Arg-Gln-Val-Cys（Disulfide bridge:Cys20-Cys26）
Hirudin (54-65) (desulfated)    Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-Gln
IELLQAR (8-branch MAPS) Selectin Binding Peptide    Ile-Glu-Leu-Leu-Gln-Ala-Arg
Kinase Domain of Insulin Receptor (4)    Thr-Arg-Asp-Ile-Tyr-Glu-Thr-Asp-Tyr-pTyr-Arg-Lys
环指蛋白17抗体价格Lys-Bradykinin-Ser-Val-Gln-Val-Ser    Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-Ser-Val-Gln-Val-Ser
MIF-1 Tyr    Tyr-Pro-Leu-Gly-NH2
Neuropeptide EI (human, mouse, rat)    Glu-Ile-Gly-Asp-Glu-Glu-Asn-Ser-Ala-Lys-Phe-Pro-Ile-NH2
Osteostatin (1-5) (human, bovine, dog, horse, mouse, rabbit, rat)    Thr-Arg-Ser-Ala-Trp
PAR-3 (1-6) amide (human)    Thr-Phe-Arg-Gly-Ala-Pro-NH2
Pneumadin (human)    Ala-Gly-Glu-Pro-Lys-Leu-Asp-Ala-Gly-Val-NH2
Protein Kinase p34(cd2) Substrate； CSH 103    Ala-Asp-Ala-Gln-His-Ala-Thr-Pro-Pro-Lys-Lys-Lys-Arg-Lys-Val-Glu-Asp-Pro-Lys-Asp-Phe
Sarafotoxin S6d    Cys-Thr-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Tyr-Phe-Cys-His-Gln-Asp-Ile-Ile-Trp
Steroidogenesis-Activator Polypeptide (rat)    Ile-Val-Gln-Pro-Ile-Ile-Ser-Lys-Leu-Tyr-Gly-Ser-Gly-Gly-Pro-Pro-Pro-Thr-Gly-Glu-Glu-Asp-Thr-Asp-Glu-Lys-Lys-Asp-Glu-Leu
TRH, Free Acid    Pyr-His-Pro