KLH conjugated synthetic peptide derived from human RING finger protein 189
规格:
0.2ml/200μg
英文名称 Anti-Rffl/RING finger protein 189 中文名称 环指蛋白189抗体品牌 别 名 CARP-2; CARP2; Caspase regulator CARP2; Caspases 8 and 10 associated RING finger protein 2; Caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin protein ligase rififylin; E3 ubiquitin-protein ligase rififylin; Fring; FYVE RING finger protein Sakura; FYVE-RING finger protein Sakura; Rffl; RFFL_HUMAN; Rififylin; RING finger and FYVE like domain containing protein; RING finger and FYVE-like domain-containing protein 1; RING finger protein 189; RING finger protein 34 like; RING finger protein 34-like; RNF189; RNF34L. 浓 度 1mg/1ml 规 格 0.2ml/200μg 抗体来源 Rabbit 克隆类型 polyclonal 交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep 产品类型 一抗 研究领域 细胞生物 信号转导 细胞凋亡 转录调节因子 蛋白分子量 predicted molecular weight: 40kDa 性 状 Lyophilized or Liquid 免 疫 原 KLH conjugated synthetic peptide derived from human RING finger protein 189 亚 型 IgG 纯化方法 affinity purified by Protein A 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 产品介绍 Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates. Subunit : Binds CASP8 and CASP10. Subcellular Location : Cytoplasm. Membrane; Peripheral membrane protein. Tissue Specificity : Ubiquitous. Detected in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. Post-translational modifications : Rapidly degraded after stimulation with TNFSF10, probably by caspases. Auto-ubiquitinated (in vitro). Palmitoylated. Similarity : Contains 1 FYVE-type zinc finger. Contains 1 RING-type zinc finger. Contains 2 SAP domains. Database links : UniProtKB/Swiss-Prot 环指蛋白189抗体品牌的功能 抗体的主要功能是与抗原(包括外来的和自身的)相结合,从而有效地清除侵入机体内的微生物、寄生虫等异物,抗体(antibody)是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活,也可能无效但有时也会对机体造成病理性损害,如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生,对人体可造成危害。 公司抗体应用于WB、IHC、IF、ELISA等实验中,环指蛋白189抗体品牌品质保证,提供完善的售前、售中、售后服务!欢迎来电咨询或联系在线客服!我们将竭诚为您服务! 环指蛋白189抗体品牌的优点: ①耐热、耐酸、耐碱、抗有机溶剂以及金属离子,稳定性好,室温下可以长期保存; ②制备简单,操作方便,可以进行批量; ③不必免疫动物,且可获得免疫动物所不能得到的“抗体”; ④可以反复使用; ⑤价格低廉。因此,设计、合成既具有类似生物抗体的高亲合性和高专一性,又具有耐热、耐酸、耐碱且又可以长期稳定的人工抗体,在部分领域替代生物抗体以进行仿生分子识别,或者完成一些生物抗体所不能完成的工作,具有重要的科学意义,在化学、生命科学和环境科学等方面具有广阔的应用前景 公司专业供应各种进口、国产一抗及二抗,品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌,品种多达7000多种,由于产品的数量众多,产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。 环指蛋白189抗体品牌具有高度的特异性,免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来,以此作为抗原或半抗原,通过免疫动物后获得特异性的抗体,再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的,因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来,以其达到对组织或细胞中的未知抗原进行定性,定位或定量的研究。 环指蛋白189抗体品牌包括以下几个步骤: 1、制备抗原。 2、选择实验动物。 3、动物免疫。 4、试取血进行测试,看看是否成功免疫。 5、如果成功免疫,杀死实验动物,采集全部血清。 6、纯化出抗体。 7、鉴定抗体。包括纯度以及特异性。 RabbitAnti-GoatIgM/PE-CY5PE-CY5标记的兔抗羊IgM规格:0.1ml GPR172BG蛋白偶联受体172B抗体规格:0.2ml RAB5ras基因家族Rab5蛋白抗体规格:0.1ml PAP1/AcidPhosphatase酸性磷酸酶抗体规格:0.2ml BSCL2/SPG17先天性脂肪代谢障碍蛋白2抗体(常染色体显性遗传痉挛性截瘫17)规格:0.2ml CDX2尾型同源盒转录因子2抗体规格:0.1ml phospho-DOK1(Tyr398)磷酸化D酪氨酸激酶衰减蛋白1抗体规格:0.1ml[Ala1]-PAR-4 (1-6) amide (mouse) Ala-Tyr-Pro-Gly-Lys-Phe-NH2 [D-Ala2] Dynorphin A (1-9), porcine Tyr-D-Ala-Gly-Phe-Leu-Arg-Arg-Ile-Arg 环指蛋白189抗体品牌[D-Phe11]-Neurotensin Pyr-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-D-Phe-Ile-Leu [His1, Lys6]-GHRP, GHRP- 6 His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 [Phe13,Tyr19]-MCH (human, mouse, rat) Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Phe-Arg-Pro-Cys-Trp-Gln-Tyr (Disulfide bridge: Cys7-Cys16) [Tyr0]-Hypercalcemia Malignancy Factor (1-40) Tyr-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Ile-Arg-Ala-Thr-Ser 26Rfa, Hypothalamic Peptide, rat Ala-Ser-Gly-Pro-Leu-Gly-Thr-Leu-Ala-Glu-Glu-Leu-Ser-Ser-Tyr-Ser-Arg-Arg-Lys-Gly-Gly-Phe-Ser-Phe-Arg-Phe-NH2 Ac-PACAP-38 (human, mouse, ovine, porcine, rat) Ac-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 Adrenorphin, Free Acid Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val