MAB<H-S-Amy>M-Tu88E8 IgG 11 543 598 103
lyophilizate
For measurement of acute pancreatitis (pancreatic α-amylase) in human
serum and urine selective blocking of salivary α-amylase isoenzyme is
achieved in the presence of the pancreatic h-α-amylase.
Application
The combination of MAB<H-S-Amy>Tu88E8 and MAB<H-S-Amy>Tu66C7
inhibits the human salivary α-amylase ≥97% while maintaining the activity of
the pancreatic h-α-amylase.
Benefits
Profit from the highly selective blocking of salivary α-amylase isoenzyme.
Product Description
Immunogen: Human salivary amylase
Spleen donor: Mouse balb/c
Antibody class: IgG 2a, kappa
Clone: Tu88E8
Properties
MAB<H-S-Amy>M-Tu88E8 IgG fraction is purified by chromatography and
lyophilized from a solution containing protein (≥20 mg/ml), potassium-phos-
phate buffer and NaCl. No preservatives are added.
Specification
Appearance: White lyophilizate
Solubility: Clear solution in NaCl, 0.9% (c=10 mg/ml)
Protein (Biuret): ≥0.7 mg/mg lyophilizate
Purity (HPLC / Mono Q): ≥90 area% IgG
Cross reactivity to h-pancreas α-amylase: ≤1 U/gW
Function testing (synergetic effects at +37°C):
h salivary amylase + MAB : ≤3% amylase activity
h pancreas amylase + MAB : ≥98% amylase activity
Stability: At -15 to -25°C within specification range for 36 months. Avoid
repeated freezing and thawing.
Literature
1) M. Gerber, K. Naujoks, H. Lenz, W. Gerhard, K. Wulff, Clin. Chem. 31, 1331
(1985)
2) M. Gerber, K. Naujoks, H. Lenz, K. Wulff, Clin. Chem. 33, 1158 (1987)