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- 详细信息
- 文献和实验
- 技术资料
- 库存:
50
- 英文名:
Human ErbB-2 ELISA Kit
- 保质期:
十二个月
- 供应商:
信裕生物
- 保存条件:
-20°C
- 规格:
96 tests
Human ErbB-2 ELISA Kit
Catalog No.: IRKTAH5100
$525
Category: Assay and ELISA Kits
Product Description
Human ErbB-2 ELISA Kit - 1 Kit (96 Wells)
Our Human ErbB-2 ELISA Kit is a sandwich ELISA intended for the quantitative determination of human ErbB-2 in cell culture supernates, serum, plasma (heparin, EDTA) and tissue homogenates.HER2/neu(also known as ErbB-2) stands for "Human Epidermal growth factor Receptor 2" and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2/neu has also been designated as CD340(cluster of differentiation 340) and p185. It is encoded by the ERBB2 gene.HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. It is encoded within the genome by HER2/neu, a known proto-oncogene. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. However, ErbB receptors dimerise on ligand binding, and HER2 is the preferential dimerisation partner of other members of the ErbB family.1 The HER2 gene is a proto-oncogene located at the long arm of human chromosome 17(17q21-q22)2.
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文献和实验Warnings And Limitations This product is for research use only. Not intended for any animal or human therapeutic or diagnostic use unless otherwise stated. Follow appropriate laboratory guidelines. This product contains 0.02% sodium azide
RAT/MOUSE GROWTH HORMONE ELISA KIT
实验原理 This assay is a Sandwich ELISA based, sequentially, on: 1) capture of rat or mouse Growth Hormone molecules from samples to the wells of a microtiter plate coated by a pre-titered amount of anti-Growth Hormone
Overexpression of erbB- 2 is important in the pathogenesis of a variety of human neoplasms. Overexpression of the erbB- 2 gene product has been associated with poor clinical prognosis with respect to malignancies originating in the ovary
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