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- ANT-139
- 以色列
- 2025年07月11日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 库存：
大量
- 英文名：
B220 (B cell specific isoform of CD45), Rat Anti-Mouse
- 保质期：
1年
- 供应商：
上海沪震实业有限公司
- 保存条件：
-20°C
- 规格：
500µg/1mg
CATALOGUE NUMBER
ANT-139
SYNONYMS
LCA, PTPRC, LY5, B220, CD45R, T200, GP180, PROTEIN-TYROSINE PHOSPHATASE, RECEPTOR-TYPE C.TYPE
Rat Anti Mouse Monoclonal.INTRODUCTION
B220 (CD45R) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.B220 (CD45R) is required for t-cell activation through the antigen receptor. The first ptpase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
CLONE
mB220.IMMUNOGEN
Purified mouse LN B cells.IG SUBCLASS
Rat IgM.PURIFICATION METHOD
Ion exchange column.FORMULATION
1mg/ml in PBS (after reconstitution).STORAGE PROCEDURES
Lyophilized: store at 4C. After reconstitution, if not intended for use within a month, aliquot and store at -20C.SOLUBILITY
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.APPLICATIONS
Staining antibody. For staining, use 10 µl/1,000,000 cells.AVAILABLE CONJUGATES
This antibody is only available as purified antibody.USAGE
Prospec's products are furnished for LABORATORY ESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
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General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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