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- 保存条件：
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 英文名：
Vitamin D Receptor / VDR Antibody (C-Terminus)
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
50 μl
产品概述：Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
靶点/蛋白：Recognizes human VDR.
来源：Rabbit
参考文献：Baker A.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:3294-3298(1988). Goto H.,et al.Biochim. Biophys. Acta 1132:103-108(1992). Rae J.L.,et al.Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases. Miyamoto K.,et al.Mol. Endocrinol. 11:1165-1179(1997). Ota T.,et al.Nat. Genet. 36:40-45(2004).
特异性：Human
别名：Vitamin D3 receptor, VDR, 1, 25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1
应用：IHC-P (5 μg/ml), WB (2.5-5 μg/ml),
简单描述：Rabbit Polyclonal Vitamin D Receptor / VDR Antibody (C-Terminus). Validated for use in WB, IHC-P.
详情：Function Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. Cellular_Location Nucleus.
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文献和实验【分享】Human press METHODS IN MOLECULAR BIOLOGY
by Minteer, Shelley D. 2005 322.Xenopus Protocols Cell Biology and Signal Transduction. Edited by Liu, X. Johné 2005 323.Arabidopsis Protocols 2 nd. Edited by Salinas, Julio 2005 324.Hormone Assays in Biological Fluids Edited by Wheeler, Michael J. 2005
Introduction to Atomic Force Microscopy (AFM) in Biology
. Green, J.D., Kreplak, L., Goldsbury, C., Li‐Blatter, X., Stolz, M., Cooper, G.S., Seelig, A., Kistler, J., and Aebi, U. 2004. Atomic force microscopy reveals defects within mica supported lipid bilayers
Bianchi, E., Steinkuhler, C., Taliani, M., Urbani, A., Francesco, R.D., and Pessi, A. 1996. Synthetic depsipeptide substrates for the assay of human hepatitis C virus protease. Anal. Biochem. 237:239‐244
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