- 询价
- invitrogen
- OPA103083
- 2025年07月15日
- Western Blot
- Rabbit
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
Phospho-GSK3 alpha/beta (Tyr279, Tyr216) Polyclonal Antibody
- 靶点：
Phospho-GSK3 alpha/beta (Tyr279, Tyr216)
- 应用范围：
Western Blot
- 宿主：
Rabbit
- 适应物种：
Human, Mouse
- 标记物：
Phosphorylated: Tyr216, Tyr279
- 克隆性：
Polyclonal
- 保存条件：
-20° C, Avoid Freeze/Thaw Cycles
- 形态：
Liquid
- 亚型：
IgG
- 免疫原：
Synthetic phosphopeptide derived from regions of human GSK3alpha/beta that contain tyrosine 279/216.
- 规格：
100 µL
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文献和实验) is accompanied with or inactivates the GSK activity. However, it is still not conclusive what the role of Tyr phosphorylation (Y216 fro beta, Y279 for alpha) on GSK activity is. One reference is a review paper published in Cell in 2001, you may take a quick
v468. chapter 4 WNT 细胞通路 检测细胞GSK3活性与表达水平
loop of the kinase domain (Tyr279 in GSK3a, andTyr216 in GSK3b), which is absolutely required for kinase activity. Thirdly, phosphorylation of GSK3 at a conserved N-terminalserine residue inhibits its kinase activity. This phosphoserine actsas
Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
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