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- 详细信息
- 文献和实验
- 技术资料
- 库存:
大量
- 英文名:
Rat NGAL (Lipocalin-2) ELISA Kit
- 保质期:
1年
- 供应商:
上海钰博生物科技有限公司
- 保存条件:
-2-8℃
- 规格:
盒
Rat NGAL (Lipocalin-2) ELISA Kit
Product Description
Rat Lipocalin-2/NGAL ELISA Kit
Our Rat Lipocalin-2/NGAL ELISA Kit is a sandwich ELISA intended for the quantitative determination of rat NGAL in cell culture supernates, serum, plasma (heparin) and urine.
Lipocalin-2(LCN2), also known as NGAL, is a protein associated with neutrophil gelatinase.1 The LCN2 gene is located at 9q34 and contains 7 exons.2 The 25-kD LCN2 protein is believed to bind small lipophilic substances such as bacteria-derived lipopolysaccharide(LPS) and formylpeptides and may function as a modulator of inflammation. NGAL tightly binds bacterial catecholate-type ferric siderophores through a cyclically permuted, hybrid electrostatic/cation-pi interaction and is a potent bacteriostatic agent in iron-limiting conditions.3 The primary LCN2 transcript is 3,696 nucleotides long, and the processed transcript is 809 nucleotides long.4 LCN2 expression in adult bone marrow, uterus, prostate, salivary gland, stomach, appendix, colon, trachea, and lung, and in fetal spleen and lung. The standard product used in this kit is recombinant rat NGAL, consisting of 177 amino acids with the molecular mass of 21kDa.
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