重组小鼠CD274(PD-L1)(B7-H1)(C端带His

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组小鼠CD274(PD-L1)(B7-H1)(C端带His标签) 分子生物学试剂在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组小鼠CD274(PD-L1)(B7-H1)(C端带His标签)
规格：10μg|50μg|500μg|1mg
品牌：百奥莱博
产地：国产|进口
英文名：Recombinant Mouse Programmed Cell Death 1 Ligand 1
编号：JN1376
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Phe19-Thr238在C端含有His标签。

CD274/PD-L1/B7-H1质量控制：＞95%(还原性SDS-PAGE)

CD274/PD-L1/B7-H1制剂：冻干品

CD274/PD-L1/B7-H1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD274/PD-L1/B7-H1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD274/PD-L1/B7-H1：
Mouse Programmed cell death 1 ligand 1(Cd274，PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.B7-H1 has been identified as one of two ligands for programmed death1 (PD1), a member of the CD28 family of immunoreceptors. B7-H1 is constitutively expressed in several organs such as heart, skeletal muscle B7-H1 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. The costimulatory function of B7-H1 is critical for enhancing maturation and differentiation of T-cells in lymphoid organs.B7-H1 expression is also induced in dendritic cells and keratinocytes after IFN gamma stimulation. Interaction of B7-H1 with PD1 results in inhibition of TCR-mediated proliferation and cytokine production. The B7-H1:PD1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.

关键词：C端带His标签,重组小鼠B7-H1,重组小鼠PD-L1,JN1376,重组小鼠CD274


除重组小鼠CD274(PD-L1)(B7-H1)(C端带His标签) 分子生物学试剂外，我公司正在打折促销以下产品：