重组小鼠趋化因子CXCL12(SDF-1)优惠

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

重组小鼠趋化因子CXCL12(SDF-1)优惠是高品质的分子生物学试剂产品，由北京百奥莱博供应，用于科研实验，本产品质量好，且极具价格优势，深为用户称道，了解更多重组小鼠趋化因子CXCL12(SDF-1)等分子生物学试剂产品请联系我司咨询订购。

名称：重组小鼠趋化因子CXCL12(SDF-1)优惠
编号：JN0321
规格：10μg|50μg|500μg|1mg
品牌：百奥莱博
产地：国产|进口
本品由我们的大肠杆菌表达系统制备，目的基因编码的Lys22-Lys89表达纯化而来。

CXCL12/SDF-1质量控制：＞95%(还原性SDS-PAGE)。

CXCL12/SDF-1制剂：冻干品

CXCL12/SDF-1保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

CXCL12/SDF-1复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于CXCL12/SDF-1：
Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, and lymphoid organs. Cxcl12 activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. It also binds to atypical chemokine receptor ACKR3 which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. Cxcl12 has several critical functions during embryonic development such as B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation. Cxcl12 plays an important role in acting as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. It stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. It also plays a protective role after myocardial infarction, induces down-regulation and internalization of ACKR3 expressed in various cells and stimulates the proliferation of bone marrow-derived b progenitor cells in the presence of IL-7 as well as growth of the stromal cell-dependent B-cell clone DW34 cells.

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重组小鼠趋化因子CXCL12(SDF-1)优惠关键词：重组小鼠趋化因子CXCL12,重组趋化因子CXCL12,重组小鼠趋化因子CXCL12蛋白,重组小鼠SDF-1,JN0321

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重组小鼠趋化因子CXCL12(SDF-1)优惠关键词：重组小鼠趋化因子CXCL12,重组趋化因子CXCL12,重组小鼠趋化因子CXCL12蛋白,重组小鼠SDF-1,JN0321


·重组人半乳糖凝集素14(Galectin-14)
编号：JN0728
英文名称：Recombinant Human Galectin-14
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met1-Asp139在C端含有His标签。

Galectin-14质量控制：＞95%(还原性SDS-PAGE)

Galectin-14制剂：液体

Galectin-14保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Galectin-14：
Galectin-14 is a member of the Galectin family of carbohydrate binding proteins. The members of Galectin family contain one or two carbohydrate recognition domains, which can bind β-Galactoside. LGALS14 is expressed intracellularly in placenta and eosinophils, and is released by eosinophils following allergen stimulation. LGALS14 may be involved in the development of allergic inflammation. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.

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