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- 文献和实验
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Human Vascular Endothelial Growth Factor A
- 库存:
719
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博主要从事生物试剂的生产和销*(代"售"),产品线涵盖重组人VEGF121(血管内皮生长因子121)厂家在内的分子生物学试剂产品,还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。
名称:重组人VEGF121(血管内皮生长因子121)厂家
编号:JN0246
品牌:百奥莱博
英文名:Recombinant Human Vascular Endothelial Growth Factor A
产地:国产|进口
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备,目的基因编码的Ala27-Arg147表达纯化而来。
VEGF121质量控制:>95%(还原性SDS-PAGE)。
VEGF121制剂:冻干品
VEGF121保存:
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。
VEGF121复溶:
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。
关于VEGF121:
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessels and endothelial cell growth, increasing microvascular permeability, promoting cell migration and inhibiting apoptosis. Alternatively spliced transcript variants of VEGF-A encod either secreted or cell-associated isoforms. The lymphangiogenesis may be promoted by upregulation of VEGF121, which may in turn act in part via induction of VEGF-C. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.
关于重组人VEGF121(血管内皮生长因子121)厂家的更详细说明,请致电我公司咨询,我们将以最饱满的热情为您提供解答,此外,我公司专业供应下列产品:
·重组人NLGN1(Neuroligin-1)(神经粘附分子)
编号:JN1163
英文名称:Recombinant Human Neuroligin-1/NLGN1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备而成(人类细胞),目的蛋白包含序列(Gln46-Val695) of Human NLGN1 在C端含有His标签。
NLGN1质量控制:>95%(SEC-HPLC,还原性SDS-PAGE)
NLGN1制剂:冻干品
NLGN1保存:
关于NLGN1:
Neuroligin-1 is a single-pass type I membrane protein and belongs to the type-B carboxylesterase/lipase family. Neuroligin-1 involves in cell-cell-interactions via its interactions with neurexin family members.It plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. It may promote the initial formation of synapses, but is not essential for this.The protein also may be involved in specification of excitatory synapses.
·重组人胞质磺基转移酶家族1A成员3(SULT1A3)
编号:JN1009
英文名称:Recombinant Human Cytosolic Sulfotransferase Family 1A Member 3
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Leu295在N端含有His标签。
SULT1A3质量控制:>95%(还原性SDS-PAGE)
SULT1A3制剂:液体
SULT1A3保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于SULT1A3:
Sulfotransferase 1A3/1A4 (SULT1A3) is 295 amino acids in length and localizes to the cytoplasm. It is a member of the Sulfotransferase 1 family. SULT1A3 can be found in the liver, colon, kidney, lung, brain, spleen, small intestine, placenta, and leukocytes. SULT1A3 exists as a homodimer and it catalyzes the sulfation of phenolic monoamines, such as dopamine, norepinephrine and serotonin, and phenolic and catecholic drugs.
重组人VEGF121(血管内皮生长因子121)厂家关键词:重组人VEGF121,重组人血管内皮生长因子121,重组VEGF121,重组人VEGF121蛋白,JN0246
·重组人CD160
编号:JN1858
英文名称:Recombinant Human CD160
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ile27-Ser159在C端含有His标签。
CD160质量控制:>95%(还原性SDS-PAGE)
CD160制剂:冻干品
CD160保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
CD160复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于CD160:
CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain. It is weakly homologous to KIR2DL4. CD160 is expressed in the spleen, peripheral blood, and small intestine. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules.
重组人VEGF121(血管内皮生长因子121)厂家关键词:重组人VEGF121,重组人血管内皮生长因子121,重组VEGF121,重组人VEGF121蛋白,JN0246
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北京百莱博科技有限公司专业生产供应销*(代"售")生物试剂、化学试剂、抗原抗体、血清血浆、Elisa试剂盒,更多试剂产品需求,欢迎来电咨询选购重组人VEGF121(血管内皮生长因子121)厂家。
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文献和实验xiazq_0 我是新手。 请问各位师兄, 1、VEGF121在什么细胞里高表达? 2、其发挥作用的基因片段是什么? 谢谢了! freecell http://ajp.amjpathol.org/cgi/content/abstract/156/4/1469 Human Vascular Endothelial Growth Factor121 (VEGF121), a 18
世界上现有单克隆抗体种类以及治癌药品 单克隆抗体(MAB)是近年来复合年增长率最大的一蛋白 类药物,2001年全球销售额增长了57.3%,接近30亿美元。在这类产品中开发主要集中在癌症治疗药物方面。预计到2010年用于癌症治疗的单克隆抗体将占其销售总额的54.7%。据预测,单克隆抗体将会以复合年增长率16.3%的速度增长,到2010年达到121.39亿美元的市场规模。其中,治疗癌症的单克隆抗体市场规模将达66.36亿美元。2003年单克隆抗体药物Herceptin(赫赛汀)销售
Angiogenic Cytokines: Quantitative and Functional Analysis
). Of these, the main isoforms VEGF121 and VEGF165 are secreted soluble glycoproteins, whereas VEGF189 and VEGF20 6 remain bound to heparan sulfate proteoglycans at the cell surface (14 ). The importance of VEGF as a potential target for antineoplastic therapy
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