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Anti-F12 Polyclonal Antibody

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  • ¥680 - 1600
  • 江蓝纯
  • K002928P
  • 2025年07月12日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      99

    • 供应商

      江蓝纯

    • 规格

      30ul/50ul/100ul

    规格:30ul产品价格:¥680.0
    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    英文名称 Rabbit F12 Polyclonal Antibody
    别名 CD123;IL3R;IL3RAY;IL3RX;IL3RY;hIL-3Ra
    应用 WB,IHC
    稀释比例 WB1:500-1:2000 IHC1:50-1:200
    交叉反应 Human,Mouse,Rat
    蛋白分子量 68kDa
    Gene ID 2161
    保存 Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
    储存液 PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 Recombinant protein of human F12
    性状 Lyophilized or Liquid
    Swiss Prot P00748
    克隆类型 Polyclonal Antibody
    来源 Rabbit
    背景资料 This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Human Anti-antibody Response

      a simple ELISA method to detect human anti-antibody response.

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