Anti-PTBP1 Polyclonal Antibody

Anti-PTBP1 Polyclonal Antibody

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  • ¥680 - 1600
  • 江蓝纯
  • K003019P
  • 2025年07月13日
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    • 详细信息
    • 技术资料
    • 库存

      99

    • 供应商

      江蓝纯

    • 规格

      30ul/50ul/100ul

    规格:30ul产品价格:¥680.0
    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    英文名称 Rabbit PTBP1 Polyclonal Antibody
    别名 CD340;HER-2;HER-2/neu;HER2;MLN 19;NEU;NGL;TKR1
    应用 WB,IHC
    稀释比例 WB1:500-1:2000 IHC1:50-1:200
    交叉反应 Human,Mouse,Rat
    蛋白分子量 57kDa
    Gene ID 5725
    保存 Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
    储存液 PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 Recombinant protein of human PTBP1
    性状 Lyophilized or Liquid
    Swiss Prot P26599
    克隆类型 Polyclonal Antibody
    来源 Rabbit
    背景资料 This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

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