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Anti-NLRP3 Polyclonal Antibody

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  • ¥960 - 1600
  • 江蓝纯
  • K004108P
  • 2025年07月16日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      99

    • 供应商

      江蓝纯

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    英文名称 Rabbit NLRP3 Polyclonal Antibody
    应用 WB,IHC
    稀释比例 WB1:500-1:2000 IHC1:50-1:200
    交叉反应 Human,Mouse,Rat
    蛋白分子量 118kDa
    Gene ID 114548
    保存 Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
    储存液 PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 Recombinant protein of human NLRP3
    性状 Lyophilized or Liquid
    Swiss Prot Q96P20
    克隆类型 Polyclonal Antibody
    来源 Rabbit
    背景资料 This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Human Anti-antibody Response

      a simple ELISA method to detect human anti-antibody response.

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