- ¥960 - 1600
- 江蓝纯
- K004885P
- 2025年07月13日
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- 详细信息
- 技术资料
- 库存：
99
- 供应商：
江蓝纯
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ¥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ¥1600.0 |
| 英文名称 | Rabbit PMS2 Polyclonal Antibody |
|---|---|
| 别名 | HNPCC4;MLH4;PMS2CL;PMSL2 |
| 应用 | WB,IHC,IF,IP |
| 稀释比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:100 IP1:20-1:50 |
| 交叉反应 | Human,Mouse,Rat |
| 蛋白分子量 | 96kDa |
| Gene ID | 5395 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PMS2 |
| 性状 | Lyophilized or Liquid |
| Swiss Prot | P54278 |
| 克隆类型 | Polyclonal Antibody |
| 来源 | Rabbit |
| 背景资料 | The protein encoded by this gene is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination. This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer. The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers, and is necessary for removal of the mismatched DNA. There is a DQHA(X)2E(X)4E motif found at the C-terminus of the protein encoded by this gene that forms part of the active site of the nuclease. Mutations in this gene have been associated with hereditary nonpolyposis colorectal cancer (HNPCC; also known as Lynch syndrome) and Turcot syndrome |
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Anti-PMS2 Polyclonal Antibody
¥960 - 1600
