Anti-WISP2 Polyclonal Antibody

Anti-WISP2 Polyclonal Antibody

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  • ¥960 - 1600
  • 江蓝纯
  • K005260P
  • 2025年07月14日
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    • 详细信息
    • 技术资料
    • 库存

      99

    • 供应商

      江蓝纯

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    英文名称 Rabbit WISP2 Polyclonal Antibody
    应用 WB,IHC
    稀释比例 WB1:500-1:2000 IHC1:50-1:200
    交叉反应 Human,Mouse,Rat
    蛋白分子量 27kDa
    Gene ID 8839
    保存 Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
    储存液 PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 Recombinant protein of human WISP2
    性状 Lyophilized or Liquid
    Swiss Prot O76076
    克隆类型 Polyclonal Antibody
    来源 Rabbit
    背景资料 This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

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