Anti-Ku70 Monoclonal Antibody

英文名称Mouse Ku70 Monoclonal Antibody别名Ku70应用WB,ICC稀释比例WB1:1000 IHC1:200交叉反应Human蛋白分子量70KDaGene ID2547保存Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 69% Glycerol.纯化方法Affinity purification亚型IgG2b免疫原Purified recombinant human Ku70 protein fragments expressed in E.coli.性状Lyophilized or LiquidSwiss ProtP12956克隆号6H10-E9-G7克隆类型Monoclonal Antibody来源Mouse背景资料The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa.The complex functions as a single-stranded DNA-dependent ATP-dependent helicase.The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair,transposition,and V(D)J recombination.High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.[provided by RefSeq,Jul 2008]