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- 详细信息
- 技术资料
- 免疫原:
见官方网站
- 亚型:
见官方网站
- 形态:
液体或冻干粉
- 保存条件:
-20°C
- 克隆性:
多克隆
- 标记物:
见官方网站
- 适应物种:
见官方网站
- 保质期:
6个月
- 抗原来源:
Synthetic
- 目录编号:
T-1220
- 级别:
高
- 库存:
大量
- 供应商:
上海信裕生物科技有限公司
- 宿主:
Synthetic
- 应用范围:
见官方网站
- 浓度:
见官方网站
- 靶点:
见官方网站
- 抗体英文名:
tBuBHQ
- 抗体名:
tBuBHQ
- 规格:
250 mg, 1 g, 5 g
tBuBHQ
DBHQA Potent Inhibitor of Sarcolasmic Reticulum Ca2+ ATPase
Cat #: T-1220
Sizes: 250 mg, 1 g, 5 g
Source: Synthetic
MW: 222.33 Da.
Target: SERCA
CLICK HERE TO RECEIVE A 250 mg FREE TRIAL SAMPLE!
tBuBHQ is a chemically synthesized compound1. It is widely used as a potent selective inhibitor of the sarcolasmic reticulum Ca2+ ATPase pump (SERCA). The pump transfers Ca2+ from the cell cytosol to the endoplasmic reticulum lumen during muscle relaxation. Inhibition of SERCA by tBuBHQ causes a dose dependent, sustained, and marked increase of cytoplasmatic Ca2+ and store operated Ca2+ depletion1. tBuBHQ also causes superoxide anion production independently of Ca2+ secretion2.
Alomone Labs is pleased to offer tBuBHQ (#T-220) a chemically synthesized compound.
References
- Ershoff BH. (1969) Proc. Soc. Exp. Biol. Med. 131, 776.
- Tsukii. K. et al. (1996) Eur. J. Pharmacol. 298, 87.
- Specifications
- Related Products
Effective concentration1-10 μM.
Chemical name2,5-ditert-butylbenzene-1,4-diol.
Molecular formulaC14H22O2.
CAS number88-58-4.
ActivitytBuBHQ is an inhibitor of the endoplasmic reticulum (ER) Ca2+-ATPase1.
Storage before reconstitutionUp to two years at room temperature.
ReconstitutionEthanol or DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to one week at 4°C.
Protect from light.
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