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- 详细信息
- 技术资料
- 免疫原:
KLH conjugated synthetic(具体详情咨询我们)
- 亚型:
IgG
- 形态:
Lyophilized or Liquid
- 保存条件:
Store at -20 °C
- 克隆性:
Polyclonal
- 标记物:
有各种标记抗体需要可以联系我公司
- 适应物种:
Hu Mo Pig Cow Hor Sheep等
- 宿主:
Rabbit
- 应用范围:
WB=1:100-500,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,Flow Cyt=1μg|Test,IF=1:100-502,
- 浓度:
1mg/ml
- 靶点:
详询
- 抗体英文名:
JNK3
- 抗体名:
氨基末端激酶3重组兔单克隆抗体
- 规格:
100ul
中文名称 氨基末端激酶3重组兔单克隆抗体
别 名 c Jun kinase 3; c-Jun N-terminal kinase 3; cJun N terminal kinase 3; FLJ12099; FLJ33785; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase; MAP kinase p49 3F12; MAPK 10; Mapk10; MGC50974; mitogen activated protein kinase 10; Mitogen-activated protein kinase 10; MK10_HUMAN; p493F12; p54bSAPK; PRKM10; protein kinase mitogen activated 10; SAPK1b; Stress activated protein kinase 1b; stress activated protein kinase beta; Stress activated protein kinase JNK3; Stress-activated protein kinase JNK3.
研究领域 肿瘤 神经生物学 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶
抗体来源 Rabbit
克隆类型 Monoclonal
克 隆 号 3A1
交叉反应 Human,
产品应用 WB=1:500-2000 ICC=1:100-500 IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
细胞定位 细胞核 细胞浆 细胞膜
性 状 Liquid
浓 度 1mg/ml
免 疫 原 Recombinant human JNK3 protein (400-500aa):
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 MAPK10 (JNK3) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuron-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 (CDK5) can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Subunit:
Interac
别 名 c Jun kinase 3; c-Jun N-terminal kinase 3; cJun N terminal kinase 3; FLJ12099; FLJ33785; JNK3 alpha protein kinase; JNK3A; MAP kinase 10; MAP kinase; MAP kinase p49 3F12; MAPK 10; Mapk10; MGC50974; mitogen activated protein kinase 10; Mitogen-activated protein kinase 10; MK10_HUMAN; p493F12; p54bSAPK; PRKM10; protein kinase mitogen activated 10; SAPK1b; Stress activated protein kinase 1b; stress activated protein kinase beta; Stress activated protein kinase JNK3; Stress-activated protein kinase JNK3.
研究领域 肿瘤 神经生物学 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶
抗体来源 Rabbit
克隆类型 Monoclonal
克 隆 号 3A1
交叉反应 Human,
产品应用 WB=1:500-2000 ICC=1:100-500 IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
细胞定位 细胞核 细胞浆 细胞膜
性 状 Liquid
浓 度 1mg/ml
免 疫 原 Recombinant human JNK3 protein (400-500aa):
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
产品介绍 MAPK10 (JNK3) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuron-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 (CDK5) can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Subunit:
Interac
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氨基末端激酶3重组兔单克隆抗体
¥2680








