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Anti-Complement factor B (huma

n)
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  • $410
  • BioPorto
  • 丹麦
  • HYB 008-020
  • 2025年07月14日
  • ELISA, WB
  • Human
  • 见官方网站
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    • 详细信息
    • 询价记录
    • 文献和实验
    • 技术资料
    • 免疫原

      见官方网站

    • 亚型

      见官方网站

    • 形态

      冻干粉或液体

    • 保存条件

      -20ºC

    • 克隆性

      多克隆

    • 标记物

      见官方网站

    • 适应物种

      见官方网站

    • 保质期

      1年

    • 抗原来源

      见官方网站

    • 目录编号

      HYB 008-020

    • 级别

      见官方网站

    • 库存

      30

    • 供应商

      上海泽叶生物科技有限公司

    • 宿主

      Human

    • 应用范围

      ELISA, WB

    • 浓度

      1 mg/ml

    • 靶点

      见官方网站

    • 抗体英文名

      Anti-Complement factor B (human)

    • 抗体名

      Anti-Complement factor B (human)

    • 规格

      200ug

    Anti-Complement factor B (human)

    Bioporto是一家体外诊断公司,专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。
    官方网站:www.bioporto.com
    Cat. No.
    HYB 008-020
    Product name
    Anti-Complement factor B (human)
    Description
    Mouse monoclonal antibody
    Specificity
    HYB 008-02 is specific for the Bb fragment of human factor B. Antibody binding abolishes the formation of C3bBb complexes.
    Immunogen
    Complement factor B purified from human plasma 
    Application
    ELISA, WB
    Species reactivity (positive)
    Human
    Species reactivity (negative)
    Not determined
    Subclass
    IgG1/k
    Gene ID
    629
    Clone number
    9B8
    Epitope
    Differs from that of HYB 008-06. Also differs from HYB 008-04 and HAV 005-02, but with slight overlap as determined by some mutual inhibition of antibody binding.
    Content
    Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
    Purification
    Protein-A purified
    Form
    Liquid
    Solvent
    0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
    Storage
    4-8ºC without exposure to light. No precautions necessary during handling.
    Target
    Factor B is a component of the alternative pathway of complement activation. The protein consists of a single polypeptide chain of molecular mass 93 kDa, and has a concentration in plasma of approximately 200 µg/mL. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Together with C3b, Bb forms the alternative pathway C3 convertase C3bBb.
    Application 1
    ELISA
    HYB 008-02 reacts strongly with human factor B. A strong reaction is seen when used as a biotinylated detection antibody in sandwich ELISA with a polyclonal capture antibody against factor B (e.g. Dako A0343).  
    Application 2
    WB
    After SDS-PAGE, HYB 008-02 reacts with the Bb fragment of factor B in its non-reduced form only. HYB 008-02 can be used for the affinity purification of human factor B, when coupled to a suitable matrix.

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