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Anti-Complement component C1s

(human, pro- and activated enzyme)
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  • $410
  • BioPorto
  • 丹麦
  • ABS 002-096
  • 2025年07月15日
  • ELISA, IHC
  • Human
  • 见官方网站
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      见官方网站

    • 亚型

      见官方网站

    • 形态

      冻干粉或液体

    • 保存条件

      -20ºC

    • 克隆性

      多克隆

    • 标记物

      见官方网站

    • 适应物种

      见官方网站

    • 保质期

      1年

    • 抗原来源

      见官方网站

    • 目录编号

      ABS 002-096

    • 级别

      见官方网站

    • 库存

      30

    • 供应商

      上海泽叶生物科技有限公司

    • 宿主

      Human

    • 应用范围

      ELISA, IHC

    • 浓度

      1 mg/ml

    • 靶点

      见官方网站

    • 抗体英文名

      Anti-Complement component C1s (human, pro- and activated enzyme)

    • 抗体名

      Anti-Complement component C1s (human, pro- and activated enzyme)

    • 规格

      200ug

    Anti-Complement component C1s (human, pro- and activated enzyme)

    Bioporto是一家体外诊断公司,专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。
    官方网站:www.bioporto.com
    Cat. No.
    ABS 002-096
    Product name
    Anti-Complement component C1s (human, pro- and activated enzyme)
    Description

    Mouse monoclonal antibody

    Specificity

    ABS 002-09 is specific for C1s proenzyme and activated free C1s

    Immunogen

    C1s proenzyme purified from human plasma

    Application
    ELISA, IHC
    Species reactivity (positive)
    Human
    Species reactivity (negative)
    Not determined
    Subclass

    IgG1/k

    Gene ID
    716
    Clone number
    9
    Epitope

    Epitope differs from that of ABS 002-49

    Content

    Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

    Purification
    Protein-A purified
    Form
    Liquid
    Solvent
    0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
    Storage
    4-8ºC without exposure to light. No precautions necessary during handling.
    Target

    C1s proenzyme is a 79.8 kDa glycoprotein produced primarily by hepatocytes but also by other cells. The proenzyme is produced as a single-chain polypeptide of 688 aa. Upon activation the peptide is cleaved between R437 and I438 giving the activated enzyme consisting of two disulfide-linked chains, A chain (52.2 kDa) and B chain (27.7 kDa). The Ca-dependent catalytic subunit of the C1 complex (C1q, C1r, C1s) comprises of two C1s and two C1r molecules and this serine protease tetramer is responsible for the initial steps in the classical complement pathway, cleavage of C4 and C2.

    Application 1

    ELISA

    ABS 002-09 reacts in ELISA when tested with activated C1s enzyme directly coated onto the microtiter well or in sandwich ELISA in combination with a polyclonal antibody in coat.
     
    Application 2

    IHC

    ABS 002-09 was used in immunohistochemistry

    产品细节图片1
    Plasma shows distinct positivity stained with ABS 002-09 on normal rectum tissue.

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