Anti-GLP-1(9-37) and GLP-1(9-3

Anti-GLP-1(9-37) and GLP-1(9-36)amide (N-terminal specific)

Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。
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Cat. No.

ABS 044-530

Product name

Anti-GLP-1(9-37) and GLP-1(9-36)amide (N-terminal specific)

Description

Mouse monoclonal antibody

Specificity

ABS 044-53 binds human GLP-1(9-36)amide 
Based on inhibition ELISA, ABS 044-53 cross-reacts <2% with GLP-1(7-36)amide

Immunogen

Synthetic GLP-1(9-18) 

Application

ELISA, WB

Species reactivity (positive)

Human

Species reactivity (negative)

Not determined

Subclass

IgG1/k

Gene ID

2641

Clone number

53

Epitope

The free N-terminus of GLP-1(9-36)amide and GLP-1(9-37)

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein-A purified

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Glucagon-like peptide-1(9-36)amide and GLP-1(9-37) are the forms of GLP-1 that result from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.

Application 1

ELISA

ABS 044-53 binds free GLP-1(9-36)amide in solution. ABS 044-53 has higher affinity for GLP-1(9-36)amide than ABS 044-49 as determined by inhibition.

Application 2

WB

ABS 044-53 can be used in Western blotting.