- $595
- BioPorto
- 丹麦
- CAM 003-072
- 2025年07月14日
- ELISA, WB, IHC
- Human
- 见官方网站
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
见官方网站
- 亚型：
见官方网站
- 形态：
冻干粉或液体
- 保存条件：
-20ºC
- 克隆性：
多克隆
- 标记物：
见官方网站
- 适应物种：
见官方网站
- 保质期：
1年
- 抗原来源：
见官方网站
- 目录编号：
CAM 003-072
- 级别：
见官方网站
- 库存：
30
- 供应商：
上海泽叶生物科技有限公司
- 宿主：
Human
- 应用范围：
ELISA, WB, IHC
- 浓度：
1 mg/ml
- 靶点：
见官方网站
- 抗体英文名：
Anti-yENaC (y−subunit epithelial sodium channel)
- 抗体名：
Anti-yENaC (y−subunit epithelial sodium channel)
- 规格：
200ug
Anti-yENaC (y−subunit epithelial sodium channel)
Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站：www.bioporto.com
- Cat. No.
- CAM 003-072
- Product name
- Anti-yENaC (y−subunit epithelial sodium channel)
- Description
-
Mouse monoclonal antibody
- Specificity
-
CAM 003-07 is specific for the inhibitory tract of human yENaC subunit.
- Immunogen
-
The inhibitory peptide from the human yENaC subunit. EAESWNSVSEGKQPRFSHRIPLC corresponding to amino acid residue 139-160 of human yENaC subunit.
- Application
- ELISA, WB, IHC
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Clone number
- 3c7
- Epitope
-
The epitope is on the inhibitory tract of human yENaC. The epitope differs from that of CAM 005-02.
- Content
-
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
-
The epithelial sodium channel (ENaC) of the kidney is necessary for extracellular volume homeostasis and normal arterial BP. Activity of ENaC is enhanced by proteolytic cleavage of the t-subunit and putative release of a 43-amino acid inhibitory tract from the y-subunit ectodomain.
- Application 1
-
ELISA
CAM 003-07 was used in ELISA. A sandwich ELISA can be made using CAM 003-07 (1-4 μg/ml) as the capture antibody and biotinylated CAM 005-02 (0.05 - 0.2 μg/ml) as the detection antibody in order to detect the peptide from the inhibitory tract (AA 138-131).
The calibration curve of a sandwich assay for Anti-yENaC using CAM 003-07 as the capture antibody and CAM 005-02B as the biotinylated detection antibody. - Application 2
-
WB
CAM 003-07 was used in Western Blot.
WB performed with CAM 003-07 on a lysate of HEK293 cells transfected with and without γENaC. Lane 1 loaded with 5µg
Lane 2 loaded with 10µg
Lane 3 loaded with 20 µg
- Application 3
-
IHC
CAM 003-07 was used in immunohistochemistry.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验CFTR Regulation of Epithelial Sodium Channel
-activated Cl− channel. Intense research following the cloning of the CFTR gene has extended the role of the CFTR beyond that of a Cl− channel. One of the best recognized, yet still controversial, functions of the CFTR is its ability to modulate
Epithelial Sodium Channel in Planar Lipid Bilayers
Amiloride-sensitive Na+ channels belong to the epithelial Na+ channel (ENaC)-degenerin superfamily of ion channels. In addition to their key role in sodium handling, they serve diverse functions in many tissues. Improper functioning of ENaC
The amiloride-sensitive epithelial Na+ channel (ENaC) is typically composed of three structurally related subunits termed α, β, and γ. We describe methods to determine the functional subunit stoichiometry of ENaC based on a biophysical
技术资料暂无技术资料 索取技术资料
