- $455
- BioPorto
- 丹麦
- CAM 011-052B
- 2025年07月15日
- ELISA
- Human
- 见官方网站
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
见官方网站
- 亚型：
见官方网站
- 形态：
冻干粉或液体
- 保存条件：
-20ºC
- 克隆性：
多克隆
- 标记物：
见官方网站
- 适应物种：
见官方网站
- 保质期：
1年
- 抗原来源：
见官方网站
- 目录编号：
CAM 011-052B
- 级别：
见官方网站
- 库存：
30
- 供应商：
上海泽叶生物科技有限公司
- 宿主：
Human
- 应用范围：
ELISA
- 浓度：
1 mg/ml
- 靶点：
见官方网站
- 抗体英文名：
Anti-Factor XII (human, heavy chain)
- 抗体名：
Anti-Factor XII (human, heavy chain)
Anti-Factor XII (human, heavy chain)
Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站：www.bioporto.com
- Cat. No.
- CAM 011-052B
- Product name
- Anti-Factor XII (human, heavy chain)
- Description
-
Mouse monoclonal antibody
- Specificity
-
CAM 011-05 binds the heavy chain of human factor XII, including factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes.
- Immunogen
-
Affinity purified human factor XII.
- Application
- ELISA
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Clone number
- 10-11-5
- Epitope
-
Differs from CAM 011-37.
- Content
-
Available in 50 µg/mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Solvent
- 0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
-
Factor XII is a component in the coagulation cascade. It is a plasma glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII to a-factor XIIa, which in turn activates factor XI to factor XIa.
- Application 1
-
ELISA
CAM 011-05B (approximately 2 μg/mL) was used as a detection antibody when used in combination with CAM 011-37 as a capture antibody (1-4 μg/mL) to measure Total factor XII, including
factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes.
The calibration curve of a sandwich assay for Anti-Factor XII using CAM 011-37 as the capture antibody and CAM 011-05B as the biotinylated detection antibody.
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文献和实验(2 ). Natural autoantibodies crossreact with a variety of conserved, and seemingly unrelated, autoantigens. Most of these antibodies are of low affinity, although rare exceptions of high affinity natural anti-DNA antibodies have been reported (3 ). The role
a simple ELISA method to detect human anti-antibody response.
多肽链延伸因子 polypeptide chain elonga－tion factor
蛋白质生物合成中参与多肽链延伸过程的蛋白质因子。从大肠杆菌等原核细胞可纯化获得三种延伸因子（elongation factor），即EFTu，EFTs和EFG，分子量大约分别为4.7万，3.6万和8.3万。EFTu与GTP结合成EFTu-GTP，然后再与氨酰tRNA结合，形成三复合体（ternary complex）氨酰-tRNA-EFTu－GTP。这种三复合体与核糖体的氨酰tRNA部位（A部位，aminoacyl site）结合，继而GTP被分解，EFTu以EFTu－
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