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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
见官方网站
- 亚型:
见官方网站
- 形态:
冻干粉或液体
- 保存条件:
-20ºC
- 克隆性:
多克隆
- 标记物:
见官方网站
- 适应物种:
见官方网站
- 保质期:
1年
- 抗原来源:
见官方网站
- 目录编号:
HYB 237-051
- 级别:
见官方网站
- 库存:
30
- 供应商:
上海泽叶生物科技有限公司
- 宿主:
Human
- 应用范围:
ELISA, WB
- 浓度:
1 mg/ml
- 靶点:
见官方网站
- 抗体英文名:
Anti-Protein C (human)
- 抗体名:
Anti-Protein C (human)
- 规格:
200ug
Anti-Protein C (human)
Bioporto是一家体外诊断公司,专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站:www.bioporto.com
- Cat. No.
- HYB 237-051
- Product name
- Anti-Protein C (human)
- Description
- Mouse monoclonal antibody
- Specificity
- HYB 237-05 reacts with human protein C.
- Immunogen
- Protein C isolated from human plasma
- Application
- ELISA, WB
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
- IgG2b/k
- Gene ID
- 5627
- Clone number
- 3C7
- Epitope
- Epitope specificity differs from that of HYB 237-01
- Content
- Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
- Protein C is a vitamin K-dependent serine protease that is produced in the liver and made up of 2 polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa inhibitng blood coagulation. The molecular weight of the active enzyme is 55kDa and the normal concentration in human plasma is approximately 1-3 ng/ml while the concentration of the proenzyme is approximately 3 µg/ml due to the very fast turnov
- Application 1
-
ELISA
HYB 237-05 binds to protein C and a reaction is seen in catching ELISA in combination with a biotin labeled antigen against protein C, but only when using a tris-buffer containing 2,5 mM CaCl2. - Application 2
-
WB
In Western blotting after SDS-PAGE HYB 237-05 reacts with protein C in non-reduced form only.
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文献和实验Mutational Analysis of the Human Protein C Gene
The single gene for protein C is located at position q13–q14 on chromosome 2 (1 ). Two groups have described human genomic clones of protein C isolated from phage l charon libraries using cDNA for human protein C as hybridization probes
Protein C (PC) is a 62-kDa vitamin K-dependent plasma zymogen which, after activation to serine protease, plays an important role in the physiologic regulation of blood coagulation. Given that PC is one of the major naturally
Anti-c-erb-B-2 Ribozyme for Breast Cancer
Our laboratory has investigated the cleavage activity of an-anti-c-erb -B-2 ribozyme. The c-erb -B-2 proto-oncogene (also called HER-2/neu ) encodes a 185 kDa transmembrane tyrosine kinase-type receptor that is homologous with the epidermal
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