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- 详细信息
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Human Growth and differentiation factor 2/Bone morphogenetic protein 9
- 库存:
660
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括重组人BMP9(GDF2)现货促销在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:重组人BMP9(GDF2)现货促销
英文名:Recombinant Human Growth and differentiation factor 2/Bone morphogenetic protein 9
规格:10μg|50μg|500μg|1mg
产地:国产|进口
品牌:百奥莱博
编号:JN1407
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser320-Arg429在C端含有His标签。
BMP9/GDF2质量控制:>95%(还原性SDS-PAGE)
BMP9/GDF2制剂:冻干品
BMP9/GDF2保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
BMP9/GDF2复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于BMP9/GDF2:
Bone morphogenetic protein 9 (BMP9), also known as growth differentiation factor-2, is a member of the TGFβ superfamily proteins that bind to type II and type I serine-threonine kinase receptors, and transduces signals through Smad and non-Smad signalling pathways. BMP9 has been shown to be a potent synergistic factor for hematopoietic progenitor generation and colony formation and may play a role in the induction and maintenance of the neuronal cholinergic phenotype in the central nervous system. ALK1 and ALK2 are important receptors for BMP9-induced osteogenic differentiation both in vitro and in vivo. BMP9 is highly expressed in the developing mouse liver, and recombinant human BMP9 stimulates hepatocyte proliferation.
更多有关重组人BMP9(GDF2)现货促销的价格及使用说明等,请联系我们的业务经理王欣女士咨询,我公司还销*(代"售")以下产品:
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重组人BMP9(GDF2)现货促销关键词:重组BMP9,JN1407,重组人GDF2,重组人BMP9蛋白
·重组人IgG1Fc
编号:JN1159
英文名称:Recombinant Human Immunoglobulin G1 Fc
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Asp104-Lys330表达纯化得来。
IgG1Fc质量控制:>95%(还原性SDS-PAGE)
IGHG1制剂:冻干品
IgG1Fc保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
IgG1Fc复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于IgG1Fc:
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.
重组人BMP9(GDF2)现货促销关键词:重组BMP9,JN1407,重组人GDF2,重组人BMP9蛋白
·重组人MMP-1(基质金属蛋白酶1)
编号:JN1680
英文名称:Recombinant Human Matrix Metalloproteinase-1
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Phe20-Asn469在C端含有His标签。
MMP-1质量控制:>95%(还原性SDS-PAGE)
MMP-1制剂:液体
MMP-1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于MMP-1:
Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP1 contains several distinct domains: a prodomain that is cleaved upon activation, a catalytic domain containing the zinc binding site, a short hinge region, and a carboxyl terminal (hemopexin like) domain. MMP-1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens as well as casein, gelatin, α1 antitrypsin, myelin basic protein, L-Selectin, pro-TNF, IL1, IGFBP3, IGFBP5, pro-MMP2, and pro-MMP9. A significant role of MMP1 is the degradation of fibrillar collagens in extracellular matrix remodeling, characterized by the cleavage of the interstitial collagen triple helix into 3/4, 1/4 fragments. MMP1 may also be involved in enzyme cascades, cytokine regulation and cell surface molecule modulation.
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