北京现货重组小鼠ULBP-1促销

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京现货重组小鼠ULBP-1促销由专业试剂供应商北京百奥莱博提供，用于生化研究，本产品质量好，且极具价格优势，深为用户称道，了解更多重组小鼠ULBP-1等分子生物学试剂产品请联系我司咨询订购。

名称：重组小鼠ULBP-1
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse UL16 Binding Protein-1/NKG2D ligand 1
产地：国产|进口
品牌：百奥莱博
编号：JN1375
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Pro26-Thr211在C端含有His标签。

ULBP-1质量控制：＞95%(还原性SDS-PAGE)

ULBP-1制剂：冻干品

ULBP-1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ULBP-1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ULBP-1：
Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocomp*(代"a")tibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. It can activate multiple signaling pathways in primary NK cells, gamma delta T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines.ULBP1 is expressed in wide range of tissues including heart, brain, lung, liver, bone marrow and some tumor cells, T-cells, B-cells, As an unconventional member of the MHC class I family, ULBP1 is able to interact with soluble CMV glycoprotein UL16 in CMV infected cells. The interaction with UL16 blocked the interaction with the NKG2D receptor, and thus might escape the immune surveillance. Furthermore, UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. The ULBP1 regulation may have implications for development of new therapeutic strategies against cancer cells.
关键词：Recombinant Mouse UL16 Binding Protein-1,重组小鼠ULBP-1蛋白,重组ULBP-1,百奥莱博,JN1375


北京现货重组小鼠ULBP-1促销正在火爆热销，除此之外，为您推荐下别热销产品：

 

编号	名称
JN0784	重组人B3GNT1
JN1699	重组人XPNPEP2
JN1354	重组小鼠Dtk
JN1017	重组人*离子胞内通道蛋白1(CLIC1)
JN0409	重组人白介素IL-2Rγ(白细胞介素2Rγ)
JN0280	重组小鼠成纤维生长因子17
JN1193	重组人排斥性导向分子a(反义导向分子a)(RGMa)
JN1316	重组小鼠CADM1(细胞粘附分子1)
JN1027	重组人IFNA4(干扰素α4)
JN0808	重组人SIAE(唾液酸O-乙酰酯酶)
JN0895	重组人NIP7
JN0398	重组人白介素17受体A( IL-17RA)
JN1304	重组人HCLS1(HS1)
JN0792	重组人HMGB2(高迁移率族蛋白B2)
JN0916	重组人ZNF22(锌指蛋白22)
JN0043	2×Fast Pfu PCR MasterMix
JN0724	重组人Parafibromin蛋白(细胞分裂周期蛋白73同源蛋白)(CDC73)
JN0915	重组人PLA2G16(磷脂酶A2-XVI)
JN0910	重组人精*酸酶2(ARG2)
JN0331	重组小鼠趋化因子CCL2(MCP-1)
JN1086	重组人胰蛋白酶1(Trypsin-1)(PRSS1)
JN0424	重组人干扰素α(βR2(IFN-α)(βR2))
JN1024	重组人TPH2(色*酸5-羟化酶2)
JN2027	重组人喹*(代"啉")酸磷酸核糖基转移酶(QPRTase)
JN1159	重组人IgG1Fc
JN1574	重组兔B7-2(CD86)
JN0233	重组人GPC5(带His标签)
JN0254	重组小鼠EGF(带His标签)
JN1766	重组人羧肽酶E(CPE)
JN0160	TEV蛋白酶
JN0457	重组人肿瘤坏死因子受体超家族成员12A(TNFRSF12A)
JN1742	重组人PRCP(溶酶体Pro-X羧肽酶)
JN0105	2×pED-T vector快速连接预混液
JN0903	重组人Toll作用蛋白(TOLLIP)
JN1007	重组人泛素结合酶E2-C(UBCE2C)
JN2010	重组人NHP2样蛋白1(NHP2L1)