北京现货重组小鼠活化白细胞粘附分子(ALCAM)(CD166

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京现货重组小鼠活化白细胞粘附分子(ALCAM)(CD166)销*(代"售")是高品质的分子生物学试剂产品，由北京百奥莱博供应，用于生化科学研究，本产品质量好，且极具价格优势，深为用户称道，了解更多重组小鼠活化白细胞粘附分子(ALCAM)(CD166)等分子生物学试剂产品请联系我司咨询订购。

名称：重组小鼠活化白细胞粘附分子(ALCAM)(CD166)
编号：JN1410
产地：国产|进口
英文名：Recombinant Mouse Activated Leukocyte Cell Adhesion Molecule
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Trp28-Lys527在C端带有Fc标签。

ALCAM /CD166质量控制：＞95%(还原性SDS-PAGE)

ALCAM /CD166制剂：冻干品

ALCAM /CD166保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ALCAM /CD166复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ALCAM /CD166：
Activated leukocyte cell adhesion molecule (ALCAM), also named as CD166 and MEMD, is a typeI transmembrane glycoprotein of immunoglobulin superfamily, which mediates homotypic and heterotypic interactions between cells. ALCAM interacts with high affinity with CD6 molecule but weaker homotypic (ALCAM–ALCAM) interactions have also been described. ALCAM–CD6 interactions play an important role in the maintenance of T cell activation, proliferation as well as in formation of immune synapse between antigen-presenting cell and lymphocytes. ALCAM is expressed on a wide variety of cells, particularly on activated lymphocytes, dendritic cells and monocytes, and on various epithelial cell types. It is also involved in multiple processes including embryogenesis, hematopoiesis, angiogenesis, and immune response. While expressed in a wide variety of tissues, ALCAM is usually restricted to subsets of cells in most adult tissues. Recently studies showed ALCAM has prognostic relevance in several human carcinomas, and it has been used as a biomarker for several tumor entities, including melanoma, gynecologic, urologic, and gastrointestinal cancers.
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