特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博供应的重组人细胞程序性死亡蛋白1(PDCD1)(PD-1)(CD279)现货用于生化科研试验,本产品质量好,且极具价格优势,深为用户称道,了解更多重组人细胞程序性死亡蛋白1(PDCD1)(PD-1)(CD279)等分子生物学试剂产品请联系我司咨询订购。
名称:重组人细胞程序性死亡蛋白1(PDCD1)(PD-1)(CD279)现货
英文名:Recombinant Human Programmed Cell Death Protein 1
规格:10μg|50μg|500μg|1mg
产地:国产|进口
品牌:百奥莱博
编号:JN0871
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu25-Gln167在C端含有His标签。
PDCD1/PD-1/CD279质量控制:>95%(还原性SDS-PAGE)
PDCD1/PD-1/CD279制剂:冻干品
PDCD1/PD-1/CD279保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
PDCD1/PD-1/CD279复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于PDCD1/PD-1/CD279:
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.
想要了解更多关于重组人细胞程序性死亡蛋白1(PDCD1)(PD-1)(CD279)现货的价格、品牌、厂家、说明书、促销信息,请和我们联系。此外我公司还销*(代"售")下面的产品:
·重组人HPGD
编号:JN0743
英文名称:Recombinant Human 15-Hydroxyprostaglandin Dehydrogenase [NAD(+)]/HPGD
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Met1-Gln266在C端含有His标签。
HPGD质量控制:>95%(还原性SDS-PAGE)
HPGD制剂:液体
HPGD保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于HPGD:
15-hydroxyprostaglandin dehydrogenase [NAD(+)], also known as Prostaglandin dehydrogenase 1, 15-PGDH, HPGD and PGDH1, belongs to the short-chain dehydrogenases/reductases (SDR) family. HPGD localizes to the cytoplasm and can be found in colon epithelium, existing as a homodimer. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. HPGD is down-regulated by cortisol, dexamethasone and betamethasone, up-regulated by TGFB1. HPGD inhibits in vivo proliferation of colon cancer cells. HPGD is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation.
重组人细胞程序性死亡蛋白1(PDCD1)(PD-1)(CD279)现货关键词:重组人CD279,重组人PDCD1,重组人细胞程序性死亡蛋白1,重组人PD-1,JN0871
·重组人羧肽酶A4(Carboxypeptidase A4)(CPA4)
编号:JN1722
英文名称:Recombinant Human Carboxypeptidase A4
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gly17-Tyr421在C端含有His标签。
Carboxypeptidase A4/CPA4质量控制:>95%(还原性SDS-PAGE)
Carboxypeptidase A4/CPA4制剂:液体
Carboxypeptidase A4/CPA4保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于Carboxypeptidase A4/CPA4:
Carboxypeptidases are zinc-containing exopeptidases that catalyze the release of carboxy-terminal amino acids, and are synthesized as zymogens that are activated by proteolytic cleavage. Carboxypeptidases cleave amino acids from the C-terminus of proteins and peptides and many are metalloproteases. They have distinct expression patterns and different specificities for example, preferentially cleaving aromatic (carboxypeptidase As) or basic (carboxypeptidase Bs) residues. Several, such as carboxypeptidase Xs, have lost their catalytic activity. Carboxypeptidases play important roles in digestion of food, processing of bioactive peptides and blood coagulation. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition.
重组人细胞程序性死亡蛋白1(PDCD1)(PD-1)(CD279)现货关键词:重组人CD279,重组人PDCD1,重组人细胞程序性死亡蛋白1,重组人PD-1,JN0871
·大片段Bst DNA聚合酶
编号:JN0022
英文名称:Bst DNA Polymerase,large fragment
规格:800U
本酶是Bacillus stearothermophilus DNA聚合酶的一部分,来源于E.coli菌株。利用基因重组技术,在大肠杆菌中进行表达后经多次纯化分离而得。该酶具有5´→3´DNA聚合酶活性,但不具有5´→3´外切核酸酶活性。
产品组成:
组份 |
JN0022-800U |
Bst DNA Pol(LF) |
800U |
10×Bst Buffer |
1ml |
产品用途:
1、富含GC序列的DNA序列测定。
2、微量(纳克量)DNA模板的快速测序等。
注意事项:
1、Bst DNA聚合酶不具有3´-5´外切酶活性。
2、长期贮存需加入100μg/ml BSA或0.1% Triton X-100。
3、建议反应温度不要超过70℃。
4、Bst DNA聚合酶不能用于热循环测序或PCR。
活性定义:65℃条件下,30分钟内使10 nmol的dNTP掺入酸不溶性沉淀物所需要的酶量定义为1个活性单位。
10×反应缓冲液:200 mM Tris-HCl,100 mM (NH4)2SO4,500 mM KCl,20 mM MgSO4,1% Tween 20,pH 8.8 储存于25℃。
反应条件:1×反应缓冲液,65℃温浴。
储存条件:-20℃
我公司正在优惠促销分子生物学试剂等系列产品,期待您的咨询选购重组人细胞程序性死亡蛋白1(PDCD1)(PD-1)(CD279)现货。